Short-Fragment Savvy. NucleoScan 2000 DNA Fragment Analyzer brings flexibility to real-time digital gel imaging

Nucleoscan 2000 DNA Fragment Analyzer In the past few years, gel electrophoresis of DNA fragments has become an important complement to hybridization and amplification sequencing tools. As variations on PCR, RFLP, mutation sequencing, and sequence and structure analysis emerge, the need for flexible gel electrophoresis systems increases. Until recently, most real-time gel imaging systems have been optimized either for ultrahigh sensitivity and noise suppression or for large-fragment sequencing

Written byDeborah Noble

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Nucleoscan 2000 DNA Fragment Analyzer

In the past few years, gel electrophoresis of DNA fragments has become an important complement to hybridization and amplification sequencing tools. As variations on PCR, RFLP, mutation sequencing, and sequence and structure analysis emerge, the need for flexible gel electrophoresis systems increases. Until recently, most real-time gel imaging systems have been optimized either for ultrahigh sensitivity and noise suppression or for large-fragment sequencing. Long runs and extensive image processing times have kept laboratories that run gels for fragment analyses from taking full advantage of on-the-fly gel imaging. But in January, NucleoTech introduced the NucleoScan 2000, a new real-time DNA gel imaging system designed specifically for fragment applications including SSCP, RFLP, AFLP, sequencing, genotyping, differential display, microsatellite analysis, and quantitative PCR.

The NucleoScan 2000 DNA Fragment Analyzer uses ultrathin gels in contact with a Peltier-controlled heat dissipation plate for tight temperature regulation (15º C to 50º ...

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