Statistics

A.F.M. Smith, G.O. Roberts, "Bayesian computation via the Gibbs sampler and related Markov-Chain Monte-Carlo methods," Journal of the Royal Statistical Society Series B, 55:3-23, 1993. Gareth Roberts (Statistical Laboratory, University of Cambridge, England): "The Markov-Chain Monte-Carlo (MCMC) methodology has been around for more than 40 years. However, until recently, its applications have been largely confined to statistical p

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

A.F.M. Smith, G.O. Roberts, "Bayesian computation via the Gibbs sampler and related Markov-Chain Monte-Carlo methods," Journal of the Royal Statistical Society Series B, 55:3-23, 1993.

Gareth Roberts (Statistical Laboratory, University of Cambridge, England): "The Markov-Chain Monte-Carlo (MCMC) methodology has been around for more than 40 years. However, until recently, its applications have been largely confined to statistical physics and image analysis.

"A very natural area of application of these techniques, especially the Gibbs sampler and the Hastings-Metropolis algorithm, is in numerical calculations for larger-dimensional posterior distributions in Bayesian statistical analyses. Our paper brings together the MCMC methodology with its natural application in Bayesian statistics. We describe the basic technique and discuss some of the important implementational and convergence issues associated with the algorithms--which necessarily produce correlated output, even after 'convergence'--from both a theoretical and a practical point of view. Key areas of application are highlighted, including problems with constrained parameters, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Related Topics

Published In

Share
Image of a man in a laboratory looking frustrated with his failed experiment.
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies