Alcoholism is a complex disorder with contributions from both genetic factors and environmental factors, such as stress. In the May 3 Science, Inge Sillaber and colleagues report the use of a genetic model to investigate stress-induced alcohol drinking in mice (Science 2002, 296:931-933).Sillaber et al. studied mice lacking the Crhr1 gene, encoding the receptor for corticotropin-releasing hormone (CRH), which has been implicated in stress-induced psychiatric disorders including alcoholism. Mutan
Alcoholism is a complex disorder with contributions from both genetic factors and environmental factors, such as stress. In the May 3
Sillaber
They performed protein profiling for glutamate receptors and found a specific upregulation of the NR2B subunit of the NMDA receptor in the
A citizen science game explores how social choices and networks can influence how an illness moves through a population.
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