artistic depiction of white, beige, and brown fat cells
Heat May Melt Away White Fat
Local heat therapy induces browning of adipose tissue in mice and humans, a study finds, suggesting it could help treat obesity—though some experts have reservations.
ABOVE: Modified from © ISTOCK.COM, Viki
Heat May Melt Away White Fat
Heat May Melt Away White Fat

Local heat therapy induces browning of adipose tissue in mice and humans, a study finds, suggesting it could help treat obesity—though some experts have reservations.

Local heat therapy induces browning of adipose tissue in mice and humans, a study finds, suggesting it could help treat obesity—though some experts have reservations.

ABOVE: Modified from © ISTOCK.COM, Viki

adipose tissue

Mouse heart cells that have taken up adipocyte-derived extracellular vesicles (stained red)
Fat Cells Send Mitochondrial Distress Signals to the Heart
Ruth Williams | Aug 20, 2021
Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.
Fat Tissue Reorganizes During Pregnancy
Catherine Offord | Aug 1, 2021
Researchers identify a protein that promotes changes in adipose tissue in vitro and in pregnant mice and may help protect against gestational diabetes in humans.
Infographic: How Pregnancy Changes Fat Tissue
Catherine Offord | Aug 1, 2021
Researchers propose a mechanism by which a protein produced in the placenta may trigger blood vessel growth and enlarge fat cells.
A bar of milk chocolate with the foil peeled back and a bite taken out
Q&A: Eating Milk Chocolate in the Morning Boosts Fat Metabolism
Amanda Heidt | Jun 30, 2021
A study of 19 postmenopausal women found that eating a bar of chocolate in the morning affected their bodies differently than eating it at night, but neither led to weight gain.
brown fat, metabolism, cardiovascular disease, cardiometabolic disease, genetics & genomics, immunology, Q&A, adipose tissue, obesity
Q&A: Brown Fat Linked to Better Cardio and Metabolic Health
Amanda Heidt | Jan 12, 2021
Paul Cohen of the Rockefeller University describes his study of thousands of people, finding that the energy-burning tissue is tied to a lower risk of for several diseases, including type 2 diabetes, high blood pressure, and heart disease.
gavel fda us stem cell adipose-derived
Judge Says FDA Can Stop Clinic from Selling Stem Cell Treatments
Emma Yasinski | Jun 7, 2019
The decision may facilitate the agency cracking down more effectively on the unproven interventions these companies sell.
Fat Tissue Can Help Cancer Cells Proliferate, Metastasize
Catherine Offord | Apr 1, 2019
Researchers disentangle how adipocytes communicate with prostate tumors in mice.
Image of the Day: Organ Crosstalk
Carolyn Wilke | Mar 19, 2019
Zooming in on the ovarioles of Drosophila could reveal links between muscles, nutrition, and the development of eggs.
Belly Fat Has a Role to Play in Fighting Infections
Selene Meza-Perez, Troy D. Randall | Oct 1, 2018
Hanging in front of the abdomen like an apron, the depot of visceral fat known as the omentum helps regulate immune responses.
Image of the Day: Fat Friendly
Sukanya Charuchandra | Jul 13, 2018
The oldest-known ice mummy consumed high amounts of fat.
Fat Cells Travel to Heal Wounds in Flies
Kerry Grens | Feb 27, 2018
Previously considered immobile, these cells swoop in to seal epithelial holes and clean up cellular detritus.  
Fat’s Influence on Cancer
Jef Akst | Apr 3, 2017
Researchers at the annual American Association for Cancer Research meeting discuss the roles of adipose tissue and inflammation in the growth and spread of tumors.
Adipocyte-Derived DNA Triggers Inflammation
Anna Azvolinsky | Mar 25, 2016
DNA released from dying fat cells stimulates inflammation within murine fat tissue. 
The Skinny on Fat Cells
Anna Azvolinsky | Nov 1, 2015
Bruce Spiegelman has spent his career at the forefront of adipocyte differentiation and metabolism.
Contributors
Karen Zusi | Nov 1, 2015
Meet some of the people featured in the November 2015 issue of The Scientist.
Breaking the Cancer-Obesity Link
Laura W. Bowers, Stephen D. Hursting, Ciara H. O’Flanagan | Nov 1, 2015
Obese people are at higher risk for developing cancer, have worse prognoses once diagnosed, and are often resistant to chemotherapy regimens. The question is, Why?
A Complex Disorder
Stephen D. Hursting, Ciara H. O’Flanagan, Laura W. Bowers | Oct 31, 2015
Factors that likely contribute to obesity include disruptions to intercellular signaling, increased inflammation, and changes to the gut microbiome.
 
Warming Up to Brown Fat
Kerry Grens | Oct 8, 2015
Scientists know how to turn on these fat-combusting cells. Can these energy burners be used to combat obesity?
Neuronal Connection Between Fat and the Brain Visualized
Anna Azvolinsky | Sep 24, 2015
Researchers pinpoint the neurons within white fat tissue that mediate brain-bound leptin signaling and eventual fat breakdown.