Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?
New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.
Is It Time to Rethink Parkinson’s Pathology?
Is It Time to Rethink Parkinson’s Pathology?

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

New evidence points to a waste-clearing problem in patients’ cells, rather than the accumulation of protein tangles, as the root cause of the neurodegenerative disease.

alpha-synuclein
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Infographic: Is Cellular Waste at the Root of Parkinson’s Disease?
Ashley Yeager | Oct 1, 2019
Damage to the lysosome, the organelle that removes excess proteins, lipids, and other materials, might be at the root of the disease.
Mouse Model Shows How Parkinson’s Disease Begins in the Gut
Mouse Model Shows How Parkinson’s Disease Begins in the Gut
Emma Yasinski | Jun 26, 2019
Johns Hopkins’s Ted Dawson discusses his lab’s demonstration that misfolded α-synuclein can move from the stomach to the brain and cause physical and cognitive symptoms.