Illustration of a transparent, blue outlined synapse with red neurotransmitters passing between them. More out-of-focus blue neurons are in the background.
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Humans and mice with a predisposition for ALS displayed altered sleep patterns before symptoms began, offering a potential novel diagnostic and treatment approach.

ALS

Photo of Ankara Jain in his lab

Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease

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Independent FDA Advisory Panel Recommends Approving ALS Drug

LAKSAMEE CAVE

Clinton Cave Investigates How Brain Cells Communicate

Motor neurons, undergoing degeneration in ALS

Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen

A conceptual 3D illustration of motor neurons degrading

Canada Approves Experimental ALS Therapy

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Brain Implant Allows Completely Paralyzed Patient to Communicate

Accurately measure a neurodegeneration biomarker from blood samples

Detecting an Accessible Biomarker of Neurodegeneration

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Same RNA Acts in Neurodegeneration and Cancer

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Infographic: Modeling Neurodegenerative Diseases with Yeast

Photographs of the October 2021 issue's contributors

Contributors

Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.

Yeast Models Provide New Insights into Neurodegenerative Diseases

Breaking Down Barriers

New Drug Combo for ALS Slows Decline in Small Clinical Study

Symptoms in ALS Mouse Model Improve with CRISPR Base Editing

“Hero” Proteins May Shield Other Proteins from Harm

Those We Lost in 2019

Commensal Bacterium Reduces ALS Symptoms in Mice

rahul desikan als amyotrophic lateral sclerosis

Neuroscientist Rahul Desikan Dies

Infographic: Human Endogenous Retroviruses and Disease

Can Viruses in the Genome Cause Disease?

Trending

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Biomedical Informatician Atul Butte Dies at 55

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An illustration showing the accumulation of amyloid plaques between nerve cells, which is the underlying cause of disorders like Alzheimer’s and Parkinson’s disease.

A Gut Pathogen’s Unexpected Weapon Against Amyloid Diseases

Image of futuristic technology such as artificial intelligence with a graphic of a robotic bird against a blue background.

An AI-Powered Scientist Proposes a Treatment for Blindness

Multimedia

Conceptual 3D illustration of mycoplasma colonies

Taking Control of Cellular Contamination with PCR Testing

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Digital microscopy image of cells in culture

Electronic Records in Cell Culture Management

Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.
June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

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Unraveling Complex Biology with Advanced Multiomics Technology

Unraveling Complex Biology with Five-Dimensional Multiomics

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Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Resurrecting Plant Defense Mechanisms to Avoid Crop Pathogens

Twist Bio 
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Seeing and Sorting with Confidence

BD
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Streamlining Microbial Quality Control Testing

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Products

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Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

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Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies

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How Alderley Analytical are Delivering eXtreme Robustness in Bioanalysis