New Drug Combo for ALS Slows Decline in Small Clinical Study
New Drug Combo for ALS Slows Decline in Small Clinical Study
After six months, patients with fast-progressing amyotrophic lateral sclerosis who had received the experimental treatment had less loss of function than those who received a placebo.
New Drug Combo for ALS Slows Decline in Small Clinical Study
New Drug Combo for ALS Slows Decline in Small Clinical Study

After six months, patients with fast-progressing amyotrophic lateral sclerosis who had received the experimental treatment had less loss of function than those who received a placebo.

After six months, patients with fast-progressing amyotrophic lateral sclerosis who had received the experimental treatment had less loss of function than those who received a placebo.

ALS
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Abby Olena | Apr 10, 2020
Researchers slowed disease progression in the mice by injecting two different viral vectors, each containing one part of the DNA encoding the Cas9 protein, to edit the causative gene.
“Hero” Proteins May Shield Other Proteins from Harm
“Hero” Proteins May Shield Other Proteins from Harm
Emma Yasinski | Mar 19, 2020
Flexible proteins appear to protect molecules from becoming denatured in extreme conditions such as heat and from clumping up, as happens in some neurodegenerative diseases.
Those We Lost in 2019
Those We Lost in 2019
Ashley Yeager | Dec 30, 2019
The scientific community said goodbye to Sydney Brenner, Paul Greengard, Patricia Bath, and a number of other leading researchers this year.
Commensal Bacterium Reduces ALS Symptoms in Mice
Commensal Bacterium Reduces ALS Symptoms in Mice
Jef Akst | Jul 24, 2019
Boosting the levels of Akkermansia muciniphila in mouse guts slowed the progression of an ALS-like disease, while two other microbiome members were associated with more severe symptoms.
Neuroscientist Rahul Desikan Dies
Neuroscientist Rahul Desikan Dies
Kerry Grens | Jul 19, 2019
He developed an MRI-based map of the human cortex, discovered genetic risk factors for neurodegenerative diseases, and wrote about his struggles with ALS.
Infographic: Human Endogenous Retroviruses and Disease
Infographic: Human Endogenous Retroviruses and Disease
Katarina Zimmer | Dec 31, 2018
Human endogenous retroviruses that colonized vertebrate DNA millions of years ago have long been dismissed as junk DNA, but researchers now know that they may play important roles in cancer, neurodegeneration, and other ailments.
Can Viruses in the Genome Cause Disease?
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Dec 31, 2018
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.
Those We Lost in 2018
Those We Lost in 2018
Ashley Yeager | Dec 26, 2018
The scientific community said goodbye to a number of leading researchers this year.
CRISPR Corrects RNA-based Disease Defects
CRISPR Corrects RNA-based Disease Defects
Kerry Grens | Aug 10, 2017
In human cells, researchers deploy the genome editor to snip out toxic repetitive sequences.