3D illustration of a neuron with the cell body highlighted in pink to represent damage from an amyloid β plaque on its axons to the left. An enlarged plaque bundle is shown in the top left corner of the image, with the fibrils highlighted in pink and yellow.

| 5 min read

Amyloid Beta Impairs Microglia Function in Alzheimer’s Disease

Dysregulated lipid metabolism in Alzheimer’s disease causes lipid buildup in microglia, reducing the immune cell’s ability to clear amyloid beta plaques.

Image of four panels. In the top panel, amyloid clusters are labeled green. There are more green clusters in the rightmost box. In the bottom panel, there is a dim arc of purple and red tau proteins on the left and a brighter arc on the right.

| 3 min read

Low Brain Lithium Leads to Alzheimer’s Disease Pathology

Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins

| 5 min read

Infographic: Secret Lives of Neurodegeneration-Linked Proteins

amyloid beta plaques

Amyloid plaques on axons of neurons

The Misunderstood Proteins of Neurodegeneration

Catherine Offord | | 10+ min read

Ramified cells in a lilac background

Could Vitamin Supplementation Help Alzheimer’s Patients?

Alejandra Manjarrez, PhD | | 8 min read

Bespectacled man wearing black shirt with arms folded looks at camera in front of lab cabinet

Neuropathologist John Trojanowski Dies at 75

Lisa Winter | | 2 min read

An APP-knockout neuron (right) shows extended axonal and reduced dendritic growth compared with a normal mouse neuron (left). Scale bar 50 µm.

Amyloid Precursor Protein Linked to Brain Development Mechanisms

Catherine Offord | | 2 min read

Illustration of neurons in white with myelin in blue

Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells

Jef Akst | | 2 min read

Colored artistic rendition of neurons and plaque buildup

Alzheimer’s Risk Gene Paradoxically Protects Against Memory Loss

Chloe Tenn | | 2 min read

Brain cells with electrical firing. 3D rendering.

Microglia as Therapeutic Targets in Neurodegenerative Diseases

Sruthi S. Balakrishnan | | 10+ min read

blue and white sign for the entrance to the FDA that says U.S. Department of Health and Human Services Food and Drug Administration

Biogen’s Alzheimer’s Drug Gets FDA Approval, Mixed Reviews

Kerry Grens | | 2 min read

A microscopy image of a mouse brain that shows the lymphatic system in bright purple and pink

Brain’s Lymphatic System Tied to Alzheimer’s Symptoms in Mice

Amanda Heidt | | 5 min read

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Trending

Kirsty Wright is searching for evidence in a missing persons investigation. She is wearing a blue shirt and glasses. Behind her is dense vegetation and police procedural tape.

How a Forensic Biologist Exposed a DNA Lab Scandal That Shook Australia

After reviewing DNA evidence from a cold case murder, Kirsty Wright uncovered systemic flaws and deception in a forensics laboratory in Queensland, Australia.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

An illustration of an in vitro fertilized embryo, which researchers recently used to study maternal aneuploidy

Genetic Basis of Aneuploidy, Which Often Causes Pregnancy Loss, Revealed

Studying over 100,000 embryos revealed genetic factors behind chromosome segregation issues that lead to aneuploidy, informing future risk screening and intervention.

Illustration of a hole in the shape of a dollar sign on a blue background. One character is falling into the hole at the bottom of the “S” while another individual is holding another up at the top of the “S”. The image represents the absence of funding for researchers in biotech with the cancellation of the SBIR/STTR program.

The Federal Government’s Research Innovation Lifeline Has Gone Dark

Congressional inaction has led to the expiration of the federal government’s SBIR/STTR program, cutting off a biotechnology lifeline.

Multimedia

Emerging Therapeutic Strategies in Oncology

Emerging Therapeutic Strategies in Oncology

In this symposium, scientists will highlight cutting-edge cancer treatments and the translational advances guiding their development.

Layered abstract design representing the structure of 3D cell models.

Transitioning to 3D Cell Models for Better Insights

Phenotypic 3D cell models incorporate tissue architectures and extracellular matrices to recapitulate the complexity of the in vivo microenvironment.

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

In this half-day virtual summit, a series of presentations will explore the scientific, regulatory, and operational factors impacting the use of in vitro NAMs in drug discovery.

Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

In this webinar, scientists will discuss innovations that are unlocking new insights into immunity.

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

In this webinar, Magdalena Pacewicz will highlight how to use AUC to characterize AAVs as part of ensuring regulatory compliance.

Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

Discover how the latest cancer research models and their applications help scientists pursue breakthrough cancer therapy research.

Products

Product News

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

The ranking places Refeyn among a cohort of high-growth UK technology firms spanning sectors including the life sciences, energy and sustainability, telecommunications, and digital technology.

Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas

Partnership unites AI and single cell technology to map immune dysfunction and improve drug discovery and development outcomes

Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

Designed to balance ease of use, cost efficiency, and reproducible data, which are critical requirements for successful high-throughput screening campaigns

SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform

Automated Twist NGS library preparation workflows available on SPT Labtech’s firefly platform via the firefly cloud