Could Vitamin Supplementation Help Alzheimer’s Patients?

Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.

Written byAlejandra Manjarrez, PhD
| 8 min read
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In 2020, nearly six million people were living with Alzheimer’s disease in the US, and that number will likely increase in the coming decades. Attempts to develop drugs to treat the neurodegenerative condition have seen limited success, with only six drugs currently approved by the FDA. Researchers have also explored the potential of existing drugs to improve the condition of people suffering from this form of dementia. Niacin, a form of vitamin B3 also known as nicotinic acid, has recently caught the attention of some researchers in the field.

The vitamin has sparked interest over the past 20 years with a few epidemiological studies that reported an association between niacin intake and a reduction in risk of general cognitive decline. More recently, researchers have begun exploring whether the compound has a positive effect on individuals with neurodegenerative diseases. Research findings published in the last few years have suggested that niacin ...

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Meet the Author

  • alejandra manjarrez

    Alejandra Manjarrez is a freelance science journalist who contributes to The Scientist. She has a PhD in systems biology from ETH Zurich and a master’s in molecular biology from Utrecht University. After years studying bacteria in a lab, she now spends most of her days reading, writing, and hunting science stories, either while traveling or visiting random libraries around the world. Her work has also appeared in Hakai, The Atlantic, and Lab Times.

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