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Two scientists look at microscopy data, and one thinks about her own images.
Right Protein, Wrong Pattern
Julia Darby’s tagged chimeric proteins told a convincing story. Later, she learned that they distorted some of the details.
Right Protein, Wrong Pattern
Right Protein, Wrong Pattern

Julia Darby’s tagged chimeric proteins told a convincing story. Later, she learned that they distorted some of the details.

Julia Darby’s tagged chimeric proteins told a convincing story. Later, she learned that they distorted some of the details.

receptor

Close-up of a mosquito antenna with hair-like protrusions and fluorescently labeled glomeruli as green circles on the shaft
The Neuroscience Behind Why Mosquitoes Always Find You
Sophie Fessl, PhD | Aug 18, 2022 | 5 min read
Neurons in mosquito antennae can express more than one olfactory receptor at a time, a redundancy that likely ensures they don’t lose a potential host’s scent.
Ramified cells in a lilac background
Could Vitamin Supplementation Help Alzheimer’s Patients?
Alejandra Manjarrez, PhD | Apr 11, 2022 | 8 min read
Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.
Discover How Protein Sequencing Evolves to Accelerate Research
The Future of Protein Sequencing
Quantum-Si | 1 min read
A new protein sequencing technology paves the way for a better understanding of protein function.
Variety of sweeteners - Stevia, sugar, pollen and honey stock photo
How the Gut Differentiates Artificial Sweeteners from Sugars
Chloe Tenn | Jan 21, 2022 | 5 min read
Signals from sweeteners and sugars are relayed from the gut to the brain by different neural pathways, a new study concludes.
black and white man on coast
Biophysicist Adrianus Kalmijn Dies at 88
Chloe Tenn | Jan 11, 2022 | 2 min read
His work revealed that sharks use an electromagnetic sense to navigate and detect prey.
hiit high intensity interval training exercise histamine receptor fexofenadine ranitidine famotidine h1 h2 receptor
Regular HIIT Exercise Enhances Health via Histamine
Rachael Moeller Gorman | Apr 21, 2021 | 4 min read
Men given high doses of two antihistamine drugs did not experience the same benefits of high intensity interval training that men on a placebo enjoyed, revealing some of the molecular underpinnings of exercise’s effect.
Why Some COVID-19 Cases Are Worse than Others
Katarina Zimmer | Feb 24, 2020 | 7 min read
Emerging data as well as knowledge from the SARS and MERS coronavirus outbreaks yield some clues as to why SARS-CoV-2 affects some people worse than others.
The Biology of Suicidal Thoughts in PTSD Patients
Catherine Offord | Sep 1, 2019 | 2 min read
Researchers link levels of a receptor in the brain to suicidal ideation in people with post-traumatic stress disorder.
How K2 and Other Synthetic Cannabinoids Got Their Start in the Lab
Ashley Yeager | Nov 27, 2018 | 7 min read
Originally intended for basic neuroscience research, the drugs were ultimately hijacked for illicit recreational use.
Image of the Day: Electrify
Sukanya Charuchandra | Aug 9, 2018 | 1 min read
Researchers have identified what makes synapses strong or weak in fruit flies.
Migraine Drug Wins EU Approval
Ashley Yeager | Jul 31, 2018 | 2 min read
Aimovig will soon be available for individuals who have four or more migraines a month.
“Public” T-Cell Receptors From Resistant People Fend Off HIV
Shawna Williams | Jun 8, 2018 | 4 min read
The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.
Genetic Adaptation to Cold Brought Migraines With It
Viviane Callier | May 3, 2018 | 3 min read
Humans living in higher latitudes tend to have a variant of a gene involved in sensing cold temperatures, but it comes with a cost.  
Immune System Targets Diverse Viruses Using the Same Small Peptide
Catherine Offord | Dec 1, 2017 | 2 min read
A single receptor on natural killer cells recognizes an amino acid sequence conserved across Zika, dengue, and related pathogens.
How Poison Frogs Avoid Poisoning Themselves
Abby Olena, PhD | Sep 21, 2017 | 4 min read
Amphibians resist their own chemical defenses with amino acid modifications in the sequence for a target receptor.
How Immune Receptors Got into Mouse Noses
Shawna Williams | Sep 1, 2017 | 2 min read
A study traces proteins’ evolution from the immune to the olfactory system.
Chemogenetics Doesn’t Work Like Many Thought
Kerry Grens | Aug 4, 2017 | 3 min read
A study finds the so-called DREADD method of manipulating neurons using a drug called CNO actually works via clozapine.
Endocannabinoids in the Groove
Megan Scudellari | Jul 16, 2017 | 2 min read
The system responsible for the buzz humans get from marijuana plays a passel of physiological roles outside the brain.
Molecular Trigger for Organ Rejection in Mice Identified
Diana Kwon | Jun 27, 2017 | 2 min read
The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  
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