Study Points to Novel Role for Microglia in Down Syndrome
Study Points to Novel Role for Microglia in Down Syndrome
Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.
Study Points to Novel Role for Microglia in Down Syndrome
Study Points to Novel Role for Microglia in Down Syndrome

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

Overactive immune cells identified in a mouse model and in postmortem human brain tissue may offer a potential therapeutic target for cognitive delays associated with the condition, researchers report.

microglia
Breaking Down Barriers
Breaking Down Barriers
The Scientist Creative Services Team | Oct 19, 2020
Looking at the future of neurodegeneration research!
T Cells and Neurons Talk to Each Other
T Cells and Neurons Talk to Each Other
Ashley Yeager | Oct 1, 2020
Conversations between the immune and central nervous systems are proving to be essential for the healthy social behavior, learning, and memory.
The Brain’s Immune Cells Stand Sentinel Against Viral Invasion
The Brain’s Immune Cells Stand Sentinel Against Viral Invasion
Ashley Yeager | Oct 1, 2020
Some viruses, possibly even SARS-CoV-2, can sneak into the brain through the nose. Recent studies show that microglia are ready for them when they do.
Infographic: How Cytokines Flow into and out of the Brain
Infographic: How Cytokines Flow into and out of the Brain
Ashley Yeager | Oct 1, 2020
Several routes exist for immune cells to communicate with neurons in the central nervous system, though T cells rarely come in direct contact with neural tissue.
How Immune Cells Make the Brain Forget
How Immune Cells Make the Brain Forget
Ashley Yeager | May 1, 2020
Microglia ingest nerve cell connections, leading to the loss of information stored in neuronal circuits.
Image of the Day: Memory Erasure
Image of the Day: Memory Erasure
Amy Schleunes | Feb 12, 2020
By trimming synapses in the adult mouse hippocampus, microglia help facilitate forgetting.
Infographic: The Neurobiology of Suicidal BehaviorInfographic: The Neurobiology of Suicidal Behavior
Infographic: The Neurobiology of Suicidal Behavior
Catherine Offord | Jan 13, 2020
Clues about the biological mechanisms that contribute to a person’s chance of contemplating or attempting suicide
What Neurobiology Can Tell Us About Suicide
What Neurobiology Can Tell Us About Suicide
Catherine Offord | Jan 13, 2020
The biochemical mechanisms in the brain underlying suicidal behavior are beginning to come to light, and researchers hope they could one day lead to better treatment and prevention strategies.
Can Viruses in the Genome Cause Disease?
Can Viruses in the Genome Cause Disease?
Katarina Zimmer | Dec 31, 2018
Clinical trials that target human endogenous retroviruses to treat multiple sclerosis, ALS, and other ailments are underway, but many questions remain about how these sequences may disrupt our biology.