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<em>The Scientist</em> poster
New Strategies for Repurposing Existing Therapies 
Drug repurposing uses existing drugs beyond the scope in which they were originally approved by the Food and Drug Administration.
New Strategies for Repurposing Existing Therapies 
New Strategies for Repurposing Existing Therapies 

Drug repurposing uses existing drugs beyond the scope in which they were originally approved by the Food and Drug Administration.

Drug repurposing uses existing drugs beyond the scope in which they were originally approved by the Food and Drug Administration.

drug repurposing

Open orange pill bottle with rounded white pills
What’s the Evidence for Fluvoxamine in COVID-19? 
Catherine Offord | May 20, 2022 | 7 min read
The US FDA’s decision not to grant an emergency use authorization for the antidepressant as a COVID-19 treatment highlights a lack of consensus among researchers about how to interpret clinical data on the drug.
Ramified cells in a lilac background
Could Vitamin Supplementation Help Alzheimer’s Patients?
Alejandra Manjarrez, PhD | Apr 11, 2022 | 8 min read
Niacin, a form of vitamin B3 used to treat cardiovascular disease, helps immune cells in the brain fight neurodegenerative diseases such as Alzheimer’s in mice models, according to recent studies. Researchers hope that human clinical trials will swiftly follow.
A photo of a triple-negative breast cancer cell
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Devin A. Reese, PhD | Mar 1, 2022 | 2 min read
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
Illustration of neurons in white with myelin in blue
Repurposed Drug Reverses Signs of Alzheimer’s in Mice, Human Cells
Jef Akst | Oct 12, 2021 | 2 min read
Researchers say they hope to launch a clinical trial to test bumetanide, a diuretic approved in 2002, but how it might improve neural functioning is unclear.
EXCLUSIVE
Assorted pills and tablets
Frontiers Pulls Special COVID-19 Issue After Content Dispute
Catherine Offord | Apr 28, 2021 | 8 min read
The issue’s guest editors resign after falling out with the publisher over the management of papers, including a rejected manuscript on ivermectin, that were submitted for a special issue on drug repurposing for COVID-19.
AI Is Screening Billions of Molecules for Coronavirus Treatments
Abby Olena, PhD | May 7, 2020 | 6 min read
Machine learning has pegged existing drugs to repurpose for COVID-19 clinical trials.
Alzheimer’s Drug Reduces Chagas Disease Infection in Mice
Emily Makowski | Dec 1, 2019 | 2 min read
The drug, called memantine, could enter clinical trials to determine its effectiveness in humans.
Ten-Minute Sabbatical
The Scientist | May 1, 2018 | 2 min read
Take a break from the bench to puzzle and peruse.
Repurposing Existing Drugs for New Indications
Anna Azvolinsky | Jan 1, 2017 | 10+ min read
An entire industry has sprung up around resurrecting failed drugs and recycling existing compounds for novel indications.
Pharma Redo
The Scientist | Dec 31, 2016 | 1 min read
Steve Braun of Cures Within Reach, a nonprofit focused on breathing new life into old medicines, describes the potential benefits of drug repurposing.
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