Artist’s rendition of multiple <em>Neisseria gonorrhoeae</em>, the bacteria that causes gonorrhea, depicted as two spheres stuck together, each covered in tendrils.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study
Gonorrhea-Blocking Mutation Also Protects Against Alzheimer’s: Study

Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.

Research traces the evolution of a gene variant that reduces the risk of Alzheimer’s disease, finding that it originally evolved in response to infectious bacteria.

autoimmunity
A twisted and folded illustration of single-stranded RNA in front of a blue background.
Deficient RNA Editing Implicated in Inflammatory Disease 
Alejandra Manjarrez | Aug 5, 2022
Genetic variants that reduce the editing levels of double-stranded RNA are associated with autoimmune and immune-mediated conditions, a study finds.
Conceptual image of a person's brain with a cluster of cells inside
Is the Immune System to Blame for Schizophrenia?
Diana Kwon | Apr 18, 2022
Several lines of evidence suggest that targeting the body’s defense pathways might help treat a subset of people with the psychiatric disorder. But many open questions remain.
Motor neurons, undergoing degeneration in ALS
Mutant T Cells That Drive Amyotrophic Lateral Sclerosis (ALS) Progression May React To a Brain Antigen
Nele Haelterman, PhD
Scientists discovered a possibly autoreactive T cell population that forecasts and supports disease progression.
Illustration comparing neural pathway and the humoral pathway
Infographic: How the Body’s Defenses Attack the Brain
Diana Kwon | Apr 18, 2022
Scientists have pinpointed several pathways through which the immune system could disrupt neuronal functioning and thereby lead to psychotic symptoms.
illustration of thymus in white on a green background
New Mechanism for Virus-Triggered Autoimmunity Uncovered
Sophie Fessl | Mar 11, 2022
Roseolovirus infection disrupts how the body trains immune cells not to attack it, a mouse study shows.
Learn How the Immune System Can Be Trained to Overcome Food Allergies
Retraining the Immune System Cavalry for Food Allergen Peacekeeping Missions
The Scientist Creative Services Team
Explore food allergy immunotherapy for reversing patient symptoms.
3D illustration of a tapeworm infestation in a human intestine
Return of the Worms
Catherine Offord | Dec 1, 2021
Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.
December 2021 - Gut Guests - Infographic
Infographic: How Worms that Reside in the Gut Could Influence Health
Catherine Offord | Dec 1, 2021
Research in animals and people supports a range of mechanisms by which the parasites affect physiology and immune responses.
Peripheral blood mononuclear cells surrounded by red blood cells in circulating blood.
Accelerating Immune Research with Cryopreserved Peripheral Blood Mononuclear Cells
The Scientist Creative Services Team and MilliporeSigma
Commerically-available peripheral blood mononuclear cells offer a well-characterized, accessible, and consistent model for immunology and therapeutic development.
a pink and purple micrograph of a longitudinal section of human spinal ganglion cells
Mouse Study Suggests Fibromyalgia Has Autoimmune Roots
Annie Melchor | Jul 2, 2021
When researchers injected mice with antibodies from fibromyalgia patients, the animals developed symptoms of the disease—suggesting that it may be controlled by the immune system, not the nervous system.
Sex Differences in Immune Responses to Viral Infection
Catherine Offord | Mar 1, 2021
Stronger interferon production, greater T cell activation, and increased susceptibility to autoimmunity are just some of the ways that females seem to differ from males.
Erika More developed a jello-like tissue system to study how immune cells stimulate tissues and blood vessel growth.
An Engineer’s Perspective on Autoimmunity
Aparna Nathan
Erika Moore builds biomaterials to study disparate lupus outcomes.
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
The Father of Autoimmunity: A Profile of Noel Rose
Diana Kwon | Jun 1, 2020
By revealing that animals could develop immune responses against their own tissues, the physician-scientist established an entirely new field of science.
Christmas background
Helping the Immune System Keep its Cool
Aparna Nathan
Researchers found that lowering the temperature alleviates autoimmunity in mice.
microbiome
Do Commensal Microbes Stoke the Fire of Autoimmunity?
Amanda B. Keener | Jun 1, 2019
Molecules produced by resident bacteria and their hosts may signal immune cells to attack the body’s own tissues.
Commensal Mimicry in Autoimmune Disease
Infographic: Commensal Mimicry in Autoimmune Disease
Amanda B. Keener | Jun 1, 2019
Antigens originating from the microbiome may trigger an autoimmune response.
40733-ts-double-edged-sword-webinar-banner-jp800x560
A Double-Edged Sword: When the Immune System Turns Against Us
The Scientist Creative Services Team
Klaus Ley and Neeloffer Mookherjee will explore the relationships between inflammation, autoimmunity, and pathology.
bacterial vaginosis vagina microbiome pregnancy prematurity
Three Studies Track People’s Microbiomes Through Health and Disease
Emma Yasinski | May 29, 2019
The second phase of the Human Microbiome Project reports on microbial composition in prediabetes, inflammatory bowel disease, and pregnancy.