CAR T Cells Treat Lupus in Mice
CAR T Cells Treat Lupus in Mice
T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.
CAR T Cells Treat Lupus in Mice
CAR T Cells Treat Lupus in Mice

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

autoimmunity
Immune Response to Gut Microbes Linked to Diabetes Risk
Immune Response to Gut Microbes Linked to Diabetes Risk
Abby Olena | Feb 1, 2019
Researchers find that it’s not just high-risk genes, but how children’s bodies respond to their own intestinal microbiota that relates to future diagnoses of type 1 diabetes.
Image of the Day: Telling Scans
Image of the Day: Telling Scans
Aggie Mika | Oct 16, 2017
In children’s brain scans, scientists uncovered signs of multiple sclerosis before the kids showed any symptoms of the disease.
The Celiac Surge
The Celiac Surge
Catherine Offord | Jun 1, 2017
A rapid increase in the global incidence of the condition has researchers scrambling to understand the causes of the trend, and cope with the consequences.
Infographic: Immune Irritation in the Gut
Infographic: Immune Irritation in the Gut
Catherine Offord | May 31, 2017
A look at how gluten affects patients with celiac disease
Key Regulator of Intestinal Homeostasis Identified
Key Regulator of Intestinal Homeostasis Identified
Diana Kwon | Mar 3, 2017
SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show. 
Sex Differences in Immune Response
Sex Differences in Immune Response
Tanya Lewis | Jun 21, 2016
Female mice lacking an immune receptor are better than males at fighting certain viral infections.
Contributors
Contributors
Catherine Offord | Jun 1, 2016
Meet some of the people featured in the June 2016 issue of The Scientist.
Toward Targeted Therapies for Autoimmune Disorders
Toward Targeted Therapies for Autoimmune Disorders
Lawrence Steinman | Jun 1, 2016
Training the immune system to cease fire on native tissues could improve outcomes for autoimmune patients, but clinical progress has been slow.
Infection-Autism Link Explained?
Infection-Autism Link Explained?
Jef Akst | Jan 31, 2016
A mouse study suggests a mechanism by which severe infections during pregnancy increase autism risk.