Stronger interferon production, greater T cell activation, and increased susceptibility to autoimmunity are just some of the ways that females seem to differ from males.

The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.

By revealing that animals could develop immune responses against their own tissues, the physician-scientist established an entirely new field of science.

Molecules produced by resident bacteria and their hosts may signal immune cells to attack the body’s own tissues.

Antigens originating from the microbiome may trigger an autoimmune response.

The second phase of the Human Microbiome Project reports on microbial composition in prediabetes, inflammatory bowel disease, and pregnancy.

T cells modified to target disease-contributing B cells improved survival in two mouse models of the autoimmune disease.

Researchers find that it’s not just high-risk genes, but how children’s bodies respond to their own intestinal microbiota that relates to future diagnoses of type 1 diabetes.

In children’s brain scans, scientists uncovered signs of multiple sclerosis before the kids showed any symptoms of the disease.

A rapid increase in the global incidence of the condition has researchers scrambling to understand the causes of the trend, and cope with the consequences.

A look at how gluten affects patients with celiac disease

SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show. 

Female mice lacking an immune receptor are better than males at fighting certain viral infections.

Meet some of the people featured in the June 2016 issue of The Scientist.

Training the immune system to cease fire on native tissues could improve outcomes for autoimmune patients, but clinical progress has been slow.

A mouse study suggests a mechanism by which severe infections during pregnancy increase autism risk. 

Researchers identify a subset of proinflammatory cytokine-producing B cells that may spark multiple sclerosis-related inflammation.  

Reviving a decades-old hypothesis of autoimmunity