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health care provider standing in front of gynecology stirrups holding swabs for Pap smear
DNA Methylation Could Predict Ovarian, Breast Cancers
A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.
DNA Methylation Could Predict Ovarian, Breast Cancers
DNA Methylation Could Predict Ovarian, Breast Cancers

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

BRCA1
buccal swab brca brca1 brca2 genetic test cancer screening uspstf
New Guidelines Expand BRCA Screening
Ashley P. Taylor | Aug 21, 2019 | 2 min read
US Preventive Services Task Force recommends genetic testing for mutations in the cancer-related genes for more—but not all—women.
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
Catherine Offord | Jul 9, 2019 | 8 min read
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
Human DNA stock photo
Setting Better Traps for PARP Inhibitors
The Scientist’s Creative Services Team and BPS Bioscience | 4 min read
An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.
Thousands of BRCA1 Genetic Variants Functionally Characterized
Sukanya Charuchandra | Sep 13, 2018 | 2 min read
The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
Vicki Brower | Apr 1, 2018 | 9 min read
With three recent FDA approvals, and a number of Phase 3 trials ongoing, the drugs are seeing a surge in interest.
First Direct-to-Consumer BRCA Test Authorized by FDA
Kerry Grens | Mar 6, 2018 | 2 min read
The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.
Genetic Risk Factors for Breast Cancer Identified
Ashley P. Taylor | Oct 23, 2017 | 4 min read
Researchers identify 72 novel genetic variants associated with breast cancer risk.
Myriad, Post Mortem
The Scientist Staff | May 31, 2016 | 1 min read
David Schwartz of the Illinois Institute of Technology-Chicago, Kent College of Law, discusses the impact of the US Supreme Court unanimously striking down Myriad Genetics' patent of human BRCA genes and tests to detect mutations in them.
BRCA1 Linked to Alzheimer’s
Jef Akst | Nov 30, 2015 | 1 min read
The cancer-related protein BRCA1 is important for learning and memory in mice and is depleted in the brains of Alzheimer’s patients, according to a study.
BRCA Breakthroughs?
Jenny Rood | Apr 21, 2015 | 2 min read
Color Genomics announces a new, lower-cost BRCA mutation test, while Inserm and Quest Diagnostics reveal plans to pool patient data to investigate rare mutations.
BRCA Mutations Mapped
Tracy Vence | Apr 7, 2015 | 1 min read
In a large study, researchers find evidence to suggest that the type and location of a woman’s BRCA1/2 mutations may affect her cancer risk.
Australian Court Upholds Patents on Human Genes
Molly Sharlach | Sep 8, 2014 | 2 min read
The Federal Court of Australia rejected an appeal of a ruling that allows companies to patent isolated human genes.
Yet Another Lawsuit over Genetic Tests
Tracy Vence | Jun 17, 2014 | 1 min read
Myriad Genetics, the company originally behind tests for the cancer-associated BRCA mutations, is suing another competitor for patent infringement.
BRCA1 Linked to Brain Size
Rina Shaikh-Lesko | Mar 20, 2014 | 1 min read
The breast cancer-associated gene may play a protective role in neural stem cells, a mouse study finds.
Another Legal Setback for Myriad
Kerry Grens | Mar 11, 2014 | 2 min read
A judge declines Myriad Genetics’s request to block its competitors from selling BRCA tests.  
Speaking of Science
The Scientist Staff | Aug 1, 2013 | 2 min read
August 2013's selection of notable quotes
Another Lawsuit over Genetic Tests
Kate Yandell | Jul 11, 2013 | 2 min read
Myriad Genetics, the company originally behind tests for the cancer-associated BRCA mutations, is suing two competitors for patent infringement.
Gene Patents Decision: Everybody Wins
Jeffrey M. Perkel | Jun 18, 2013 | 5 min read
Last week’s Supreme Court decision to invalidate patents on human genes was a win for patients, independent researchers, and even the wider biotech industry.
Supreme Court Nixes Patenting Human Genes
Dan Cossins | Jun 13, 2013 | 2 min read
The Justices have decided that isolated sequences of human DNA are not eligible for patent protection, but rules that artificial sequences can be patented.
 
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