New Guidelines Expand <em>BRCA</em> Screening
New Guidelines Expand BRCA Screening
US Preventive Services Task Force recommends genetic testing for mutations in the cancer-related genes for more—but not all—women.
New Guidelines Expand BRCA Screening
New Guidelines Expand BRCA Screening

US Preventive Services Task Force recommends genetic testing for mutations in the cancer-related genes for more—but not all—women.

US Preventive Services Task Force recommends genetic testing for mutations in the cancer-related genes for more—but not all—women.

BRCA1
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
MyHeritage Launches Health-Related Genetic Test, Ignites Debate
Catherine Offord | Jul 9, 2019
Its screen for selected variants of some disease-linked genes gives customers an incomplete picture of their risk—do they know?
Thousands of <em>BRCA1</em> Genetic Variants Functionally Characterized
Thousands of BRCA1 Genetic Variants Functionally Characterized
Sukanya Charuchandra | Sep 13, 2018
The researchers catalogued 3,893 variants of the gene implicated in cancer using CRISPR.
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
PARP Inhibitors Are Improving the Outlook of Hard-to-Treat Cancers
Vicki Brower | Apr 1, 2018
With three recent FDA approvals, and a number of Phase 3 trials ongoing, the drugs are seeing a surge in interest.
First Direct-to-Consumer BRCA Test Authorized by FDA
First Direct-to-Consumer BRCA Test Authorized by FDA
Kerry Grens | Mar 6, 2018
The agency gave personal genomics company 23andMe the green light to screen samples for breast cancer–related genetic mutations.
Genetic Risk Factors for Breast Cancer Identified
Genetic Risk Factors for Breast Cancer Identified
Ashley P. Taylor | Oct 23, 2017
Researchers identify 72 novel genetic variants associated with breast cancer risk.
Myriad, Post Mortem
Myriad, Post Mortem
The Scientist Staff | May 31, 2016
David Schwartz of the Illinois Institute of Technology-Chicago, Kent College of Law, discusses the impact of the US Supreme Court unanimously striking down Myriad Genetics' patent of human BRCA genes and tests to detect mutations in them.
BRCA1 Linked to Alzheimer’s
BRCA1 Linked to Alzheimer’s
Jef Akst | Nov 30, 2015
The cancer-related protein BRCA1 is important for learning and memory in mice and is depleted in the brains of Alzheimer’s patients, according to a study.
BRCA Breakthroughs?
BRCA Breakthroughs?
Jenny Rood | Apr 21, 2015
Color Genomics announces a new, lower-cost BRCA mutation test, while Inserm and Quest Diagnostics reveal plans to pool patient data to investigate rare mutations.
<em>BRCA</em> Mutations Mapped
BRCA Mutations Mapped
Tracy Vence | Apr 7, 2015
In a large study, researchers find evidence to suggest that the type and location of a woman’s BRCA1/2 mutations may affect her cancer risk.
Australian Court Upholds Patents on Human Genes
Australian Court Upholds Patents on Human Genes
Molly Sharlach | Sep 8, 2014
The Federal Court of Australia rejected an appeal of a ruling that allows companies to patent isolated human genes.
Yet Another Lawsuit over Genetic Tests
Yet Another Lawsuit over Genetic Tests
Tracy Vence | Jun 17, 2014
Myriad Genetics, the company originally behind tests for the cancer-associated BRCA mutations, is suing another competitor for patent infringement.
<em>BRCA1</em> Linked to Brain Size
BRCA1 Linked to Brain Size
Rina Shaikh-Lesko | Mar 20, 2014
The breast cancer-associated gene may play a protective role in neural stem cells, a mouse study finds.
Another Legal Setback for Myriad
Another Legal Setback for Myriad
Kerry Grens | Mar 11, 2014
A judge declines Myriad Genetics’s request to block its competitors from selling BRCA tests.  
Speaking of Science
Speaking of Science
The Scientist Staff | Aug 1, 2013
August 2013's selection of notable quotes
Another Lawsuit over Genetic Tests
Another Lawsuit over Genetic Tests
Kate Yandell | Jul 11, 2013
Myriad Genetics, the company originally behind tests for the cancer-associated BRCA mutations, is suing two competitors for patent infringement.
Gene Patents Decision: Everybody Wins
Gene Patents Decision: Everybody Wins
Jeffrey M. Perkel | Jun 18, 2013
Last week’s Supreme Court decision to invalidate patents on human genes was a win for patients, independent researchers, and even the wider biotech industry.
Supreme Court Nixes Patenting Human Genes
Supreme Court Nixes Patenting Human Genes
Dan Cossins | Jun 13, 2013
The Justices have decided that isolated sequences of human DNA are not eligible for patent protection, but rules that artificial sequences can be patented.
 
Why Women’s Eggs Don’t Last
Why Women’s Eggs Don’t Last
Kate Yandell | Feb 13, 2013
As reproductive tissues age, DNA repair mechanisms become less efficient, causing genomic damage to accumulate.
Should Human Genes be Patented?
Should Human Genes be Patented?
Edyta Zielinska | Dec 3, 2012
The Supreme Court agrees to hear a case deciding if two cancer genes should continue to be protected by patent.