Stop the Variant, Save the Channel
Stop the Variant, Save the Channel
By using antisense oligonucleotides to inhibit a mutated exon associated with Timothy syndrome mutation, researchers restored neuron function.
By using antisense oligonucleotides to inhibit a mutated exon associated with Timothy syndrome mutation, researchers restored neuron function.
calcium
Inducing Cardiomyocyte Maturation
Jennifer Zieba, PhD | Aug 1, 2023 | 2 min read
By combining calcium and electrical pacing, researchers designed a scalable protocol for culturing mature cardiac tissues from induced pluripotent stem cells.
Image of the Day: Actin Burst
The Scientist and The Scientist Staff | Dec 6, 2017 | 1 min read
Researchers are looking at actin polymerization and calcium uptake in human cells to study mitochondrial division.
Not So Noncoding
Jenny Rood | Jun 1, 2015 | 2 min read
An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.
Crack Control
Dan Cossins | Mar 1, 2013 | 2 min read
Nanoscale cracks in bone dissipate energy to protect against fracture, a process that appears to be regulated by the interaction of two proteins.
Flickering Neurons
Ruth Williams | Feb 1, 2013 | 3 min read
Fluorescent calcium sensors in transgenic mice give a real-time readout of neuronal activity.
Calcium and the Pancreas
Ole H. Petersen, Oleg V. Gerasimenko, and Julia V. Gerasimenko | Feb 1, 2012 | 1 min read
Normal pancreatic function depends on the precise flow of calcium within and into the acinar cells of the organ.
The War Within
Ole H. Petersen, Oleg V. Gerasimenko, and Julia V. Gerasimenko | Feb 1, 2012 | 9 min read
Unraveling the molecular causes of acute pancreatitis—a potentially deadly disease in which the pancreas essentially digests itself—is yielding clues to how it might be treated.