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A young child with Down syndrome at the dentist.
| 4 min read
Disrupted calcium signaling could be linked to low saliva production and gum disease in Down syndrome, indicating potential therapeutic targets to boost oral health.

calcium signaling

A colored microscopy image showing cells that are dying in yellow and healthy cells in blue 

Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies

Measure Intracellular Calcium in Live Cells

From Imaging to Kinetics: Measuring Calcium Signaling

Live-cell Imaging

Image of the Day: Muting Muscle Spasms

Image of the Day: Calcium Signaling

Image of the Day: Actin Burst

How Hot Peppers Can Ease Pain

The Energizer

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A team of cartoon scientists studying a giant pancreas.

Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch

A magnifying glass, representing increased scrutiny into this student’s publication record, leans against a stack of papers.

Student Admits She Did Not Conduct Experiments in Now-Retracted Paper

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An Indian farmer ploughs his fields with two oxen while barefoot, a risk factor for mycetoma infection.

Mycetoma: The Invisible Disease Beneath India's Soil

Multimedia

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

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Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

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Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad
Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

Beyond the Basics: Strategies for Single-Cell and Spatial Transcriptomics Analysis

bioxcell
Scientist reviewing cellular and molecular data on a computer in a laboratory.

Building Translation-Ready Biomarkers with Connected Workflows

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Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

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Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

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CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
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Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays