cancer biology
Tracking the Evolutionary History of a Tumor
Tracking the Evolutionary History of a Tumor
Amber Dance | Apr 1, 2017
Analyzing single cell sequences to decipher the evolution of a tumor
Gel Scaffolds for Delivery of Immunotherapies
Gel Scaffolds for Delivery of Immunotherapies
Rachel Berkowitz | Apr 1, 2017
Using biocompatible polymers to carry cancer immune therapies directly to the tumor
Location, Location, Location
Location, Location, Location
Anna Azvolinsky | Apr 1, 2017
Since first proposing that a cell’s function and biology depend on its surroundings, Mina Bissell continues to probe the role of the extracellular matrix.
Neoantigens Enable Personalized Cancer Immunotherapy
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
How Cancers Evolve Drug Resistance
How Cancers Evolve Drug Resistance
Anna Azvolinsky | Apr 1, 2017
Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.
Infographic: Targeting Cancer Antigens
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.
DNA Replication Errors Contribute to Cancer Risk
DNA Replication Errors Contribute to Cancer Risk
Anna Azvolinsky | Mar 23, 2017
A follow-up study confirms that random mutations acquired during normal stem cell division likely play a major role in cancer incidence.
Non-Chromosomal DNA Drives Tumor Evolution
Non-Chromosomal DNA Drives Tumor Evolution
Anna Azvolinsky | Feb 8, 2017
Researchers discover that short pieces of DNA harboring oncogenes are relatively widespread in cancer.
Lipids Take the Lead in Metastasis
Lipids Take the Lead in Metastasis
Amanda B. Keener | Jan 20, 2017
Researchers find diverse ways that the molecules can regulate cancer’s spread.
Peter Nowell, Co-Discoverer of the Philadelphia Chromosome, Dies
Peter Nowell, Co-Discoverer of the Philadelphia Chromosome, Dies
Diana Kwon | Jan 9, 2017
The tumor biologist’s landmark discovery provided the first clear evidence that genetic mutations could lead to cancer, and gave rise to a crucial cancer drug.