cancer biology

In vitro and mouse experiments show how cancer cells forced through tiny pores—mimicking the physical experience of metastasis—resisted programmed cell death and avoided detection by the immune cells that would normally kill them.

Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.

New research in mice reveals why natural killer cells, normally effective at hunting cancer, are sometimes stopped in their tracks.  

Unsatisfied by how treatments for childhood leukemia failed to prevent the disease’s return, Pinkel combined them all—and virtually cured the disease.

A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.

From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.

A study uncovers a novel connection between the biomolecule and cancer progression.

When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.

Selected Images of the Day from the-scientist.com

Mintz’s experiments over her six-decade career were foundational to cancer and genetics research.

From a Nobel prize and photosynthesis-powered brains to neurodegeneration research and controversy over a new Alzheimer’s drug, a look back at some of the biggest brain-related developments of the year.

This year revealed just how much scientists have learned about the disease, from how animals become naturally cancer-resistant to how tumor cells harness extracellular DNA to develop rapid drug resistance.

Researchers involved in an eight-year project to reproduce the findings of more than 50 high-impact papers struggled to get enough information to even carry out most of the experiments.

The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.