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A mole-rat poses in the grass
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats
Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats
The Scientist Speaks - Exploring the Secrets to Longevity and Cancer Resistance in Mole-Rats

Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 

Vera Gorbunova discusses what naked and blind mole-rat cells reveal about aging and cancer resistance mechanisms. 

cancer resistance
Salmonella (pink) invading a human epithelial cell (yellow)
Modified Salmonella Revs Immune Response, Combats Tumors in Mice
Natalia Mesa, PhD | Feb 3, 2022 | 5 min read
When coated with positively charged particles, the bacteria shuttled antigens out of tumors and activated the immune system, a study finds.
fingertips with pills on them
Over-the-Counter Antihistamines Could Help Against Cancer
Alejandra Manjarrez, PhD | Nov 24, 2021 | 3 min read
The binding of histamine with one of its receptors within the tumor environment makes cancer cells more resistant to immunotherapy, according to a new study. Blocking that binding could improve responses to treatment.
blind mole rat
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021 | 3 min read
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
A tasmanian devil with its nose in the air
Deadly Facial Tumors Spur Tasmanian Devil Evolution: Study
Christie Wilcox, PhD | Jun 16, 2021 | 6 min read
The largest study to date of the animals’ genetics provides robust evidence that they are adapting to survive a highly lethal, contagious cancer scientists feared would cause their extinction.
José Baselga, cancer, research, oncology, AstraZeneca, breast cancer, drugs, therapeutics, obituary, dies
José Baselga, Renowned Oncologist, Dies at 61
Asher Jones | Mar 22, 2021 | 2 min read
The cancer researcher and executive vice president of AstraZeneca’s oncology research and development is well known for his role in the development of pivotal breast cancer therapies.
Mutant RAS Proteins Team Up for Oncogenicity
Jim Daley | Apr 1, 2018 | 2 min read
Mice with cancer whose KRAS proteins couldn’t link together had much better survival outcomes than those whose oncogenic mutant paired with wild-type KRAS.
Cancers Relapse by Feeding Off Immune Signals
Shawna Williams | Oct 16, 2017 | 2 min read
In mice, the tumor cells are able to thwart the immune response that would kill them—but immunotherapy prevented the return of melanoma.
How Cancers Evolve Drug Resistance
Anna Azvolinsky | Apr 1, 2017 | 10+ min read
Researchers unravel the sophisticated ways cancers evade treatments, including immunotherapies, designed to destroy them.
Infographic: Mechanisms of Resistance
Anna Azvolinsky | Mar 31, 2017 | 1 min read
Cancers appear to be able to evolve resistance to many of the therapies doctors have tried.
Cancer Detected in Naked Mole Rats
Kerry Grens | Feb 8, 2016 | 1 min read
Two captive males of the cancer-resistant species have shown signs of malignant tumors.
Explaining Elephants’ Cancer Resistance
Jef Akst | Oct 13, 2015 | 2 min read
Two studies reveal that the giant mammals have dozens of extra copies of a cancer-preventing gene.
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