A brazier and charred stones, thought to be part of burial ceremonies, preserve signs that people used the drug thousands of years ago.

Whether due to a changing regulatory climate, positive results from early clinical trials, or simply a desire to untangle cannabis’s mythology, scientists have rediscovered cannabis after ignoring it for decades. Find out how a plant's genetic signature translates into a compound profile!

Genes inserted into the yeast genome produce the compounds CBD and THC in the microbes.

Rodent and human studies have revealed a multitude of effects starting during gestation and lasting into adulthood.

Originally intended for basic neuroscience research, the drugs were ultimately hijacked for illicit recreational use.

Young rats injected with a synthetic cannabinoid have more of the brain’s motivating dopaminergic signaling and fewer numbers of inhibitory neurons than controls.

Offspring of rats exposed to vaporized cannabis had difficulty switching strategies to get a sugar reward, according to a study presented at the Society for Neuroscience conference.

Epidiolex, a cannabis-derived medicine for epilepsy, will prompt federal regulatory changes that could crack open access to study the plant.

NIDA pharmacologist Michael Baumann explains how “unscrupulous vendors” hijacked compounds used in neuroscience and turned them into dangerous drugs.