Originally intended for basic neuroscience research, the drugs were ultimately hijacked for illicit recreational use.

Young rats injected with a synthetic cannabinoid have more of the brain’s motivating dopaminergic signaling and fewer numbers of inhibitory neurons than controls.

Offspring of rats exposed to vaporized cannabis had difficulty switching strategies to get a sugar reward, according to a study presented at the Society for Neuroscience conference.

Epidiolex, a cannabis-derived medicine for epilepsy, will prompt federal regulatory changes that could crack open access to study the plant.

NIDA pharmacologist Michael Baumann explains how “unscrupulous vendors” hijacked compounds used in neuroscience and turned them into dangerous drugs.

Marijuana ointments as cancer treatments remain a distant prospect. 

And the same endocannabinoid system that translates marijuana's buzz-inducing compounds into a high plays crucial roles in health and disease outside the brain.

In young mice, THC had the opposite effect.

Academics partner with a biotech firm to investigate cannabinoids and develop potential therapeutics.