Gene Editing Makes Cells Evade Immune Attack In Vitro
Gene Editing Makes Cells Evade Immune Attack In Vitro
To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.
Gene Editing Makes Cells Evade Immune Attack In Vitro
Gene Editing Makes Cells Evade Immune Attack In Vitro

To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.

To advance the possibility of off-the-shelf cardiac cell therapies, scientists devise an engineered cardiac stem cell that avoids stimulating a detrimental immune attack.

cardiac stem cell
<em>The Lancet</em> Retracts Cardiac Stem Cell Clinical Trial Paper
The Lancet Retracts Cardiac Stem Cell Clinical Trial Paper
Kerry Grens | Mar 14, 2019
The publication of the SCIPIO trial is among many by Piero Anversa’s lab that Harvard Medical School flagged for fraudulent data.
<em>Circulation Research&nbsp;</em>Fires Editor over Homophobic Email
Circulation Research Fires Editor over Homophobic Email
Carolyn Wilke | Mar 11, 2019
Roberto Bolli was editor of the American Heart Association’s journal until last week, after anti-gay comments he sent to the Louisville Ballet became public.
The Biggest Science News of 2018
The Biggest Science News of 2018
Kerry Grens | Dec 27, 2018
From disastrous scientific setbacks to the upending of scientific dogma and the end of a 40-year search for a protein
Journals Retract 13 Papers from Heart Stem Cell Lab
Journals Retract 13 Papers from Heart Stem Cell Lab
Kerry Grens | Dec 14, 2018
It’s the latest fallout from an investigation by Harvard and Brigham and Women’s into work overseen by Piero Anversa.
Image of the Day: Scarred Hearts
Image of the Day: Scarred Hearts
Ashley Yeager | Dec 4, 2018
Maps of diving cells before and after heart attacks in mice offer additional evidence against the existence of cardiac stem cells.
Heart Cell Therapy Trial Paused After Fraud Allegations
Heart Cell Therapy Trial Paused After Fraud Allegations
Ashley P. Taylor | Oct 30, 2018
A trial to test whether so-called c-kit cardiac stem cells, first reported by Piero Anversa, could help patients with chronic heart failure has been halted in light of suspicion surrounding his work.
Dozens of Retractions Requested for Heart Stem Cell Studies
Dozens of Retractions Requested for Heart Stem Cell Studies
Ashley P. Taylor | Oct 15, 2018
Harvard and Brigham and Women’s Hospital disavow the work by former faculty member Piero Anversa.
Adult Cardiac Stem Cells Don&rsquo;t Exist: Study
Adult Cardiac Stem Cells Don’t Exist: Study
Diana Kwon | Sep 5, 2018
A mouse study adds to the growing body of work disputing the ability of progenitor cells to regenerate muscle tissue in adult mammals’ hearts.
Infographic: How to Make an Artificial Stem Cell
Infographic: How to Make an Artificial Stem Cell
Diana Kwon | May 31, 2017
See researchers' recipe for synthetic mesenchymal stem cells, which showed cardiac regenerative potential in mice.
Mysterious Mechanisms of Cardiac Cell Therapy
Mysterious Mechanisms of Cardiac Cell Therapy
Kerry Grens | Feb 4, 2016
Injections of progenitor cells into damaged rat hearts may improve function, but not because the implants themselves are creating new muscle.
Latest in Heart Stem Cell Debate
Latest in Heart Stem Cell Debate
Kerry Grens | Oct 26, 2015
Given the right environment, cKit+ cells from the mouse heart can develop into new cardiac muscle, according to a study.
Regenerative Cardiomyocytes Found
Regenerative Cardiomyocytes Found
Kerry Grens | Jun 24, 2015
Specialized cardiac cells in the mouse heart appear to be the long-sought-after proliferative heart cells.
Hearts on Trial
Hearts on Trial
Kerry Grens | May 1, 2015
As researchers conduct the most rigorous human trials of cardiac cell therapies yet attempted, a clear picture of whether these treatments actually work is imminent.
Heart Strings
Heart Strings
The Scientist Staff | Apr 30, 2015
An animated primer on the harvesting, growth, and administration of cardiac cells to heart attack patients
More Doubt Cast Over Cardiac Stem Cells
More Doubt Cast Over Cardiac Stem Cells
Kerry Grens | May 7, 2014
Contrary to previous reports, cell lineage tracing reveals stem cells in the heart rarely contribute to new muscle.
Exosomes Vital for Heart Repair
Exosomes Vital for Heart Repair
Kerry Grens | May 6, 2014
Reparations after a heart attack in mice depend not on stem cells, but on the exosomes they secrete.