Macrophages in Mice Shuttle Mitochondria to Neurons in Need
Macrophages in Mice Shuttle Mitochondria to Neurons in Need
The findings could represent a novel mechanism for relieving inflammatory pain.
Macrophages in Mice Shuttle Mitochondria to Neurons in Need
Macrophages in Mice Shuttle Mitochondria to Neurons in Need

The findings could represent a novel mechanism for relieving inflammatory pain.

The findings could represent a novel mechanism for relieving inflammatory pain.

chronic pain
Image of the Day: Viral Residue
Image of the Day: Viral Residue
Nicoletta Lanese | Aug 30, 2019
Genetic material from the chikungunya virus remains in mouse cells after infection and may be linked to later joint pain.
Special Schwann Cells in Mice Play Unsung Role in Pain
Special Schwann Cells in Mice Play Unsung Role in Pain
Nicoletta Lanese | Aug 16, 2019
The glia seem to make up part of a newly described sensory organ, the discoverers suggest.
Men React to Repeated Painful Experiences Differently than Women Do
Men React to Repeated Painful Experiences Differently than Women Do
Diana Kwon | Jan 14, 2019
Men’s pain tolerance decreases when exposed to a setting where they’ve previously had a painful experience.
Synthetic Botox Treats Chronic Pain in Mice
Synthetic Botox Treats Chronic Pain in Mice
Abby Olena | Jul 18, 2018
Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.
Contributors
Contributors
Jef Akst and Katarina Zimmer | Dec 31, 2017
Meet some of the people featured in the January 2018 issue of The Scientist.
Prizes and Penalties
Prizes and Penalties
Bob Grant | Dec 31, 2017
Life is filled with pleasure and pain. Science and society are struggling mightily with both.
Targeting Sodium Channels for Pain Relief
Targeting Sodium Channels for Pain Relief
Catherine Offord | Dec 31, 2017
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Glial Ties to Persistent Pain
Glial Ties to Persistent Pain
Mark R. Hutchinson | Dec 31, 2017
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Infographic: A Painful Pathway
Infographic: A Painful Pathway
Catherine Offord | Dec 31, 2017
Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.