Many spiral-shaped orange Borrelia bacteria.
| 3 min read
Cell wall components from Borrelia burgdorferi lingered in the mouse liver for weeks, suggesting new therapeutic avenues for this chronic disease.

chronic pain

Human hand with white glove holding a white mouse in a green background.

Study Traces a Neural Circuit Behind Green Light–Mediated Pain Relief

red ants coming out of dirt hole

Bull Ant Venom Evolved to Make Bites More Painful to Mammals

Illustration of peach-colored microglia among light blue neurons. Both cell types are illustrated with multiple jagged extensions coming out of a spherical cell body.

Mouse Immune Cells Destroy Nerves’ Coating, Causing Chronic Pain

Grey and white stones on a wooden plank, symbolic of brain meditation.

How Meditation Changes the Brain: New Study Challenges Popular Beliefs

Giannina Descalzi

Giannina Descalzi Studies the Factors Underlying Chronic Pain

Senior woman wearing a grey pullover sitting on a bed and holding her back.

Early Inflammation Protects Against Chronic Pain, Study Finds

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Ophthamologist Alan Scott Dies at Age 89

Rounded red and green fluorescent cells are visible on a light and dark gray background

Neurons Firing Together Generate Spontaneous Pain

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From Bench to Boardroom

morphine drip

Morphine Tolerance Pathway Identified in Mice

two doctors looking at a medical monitor showing electrodes being inserted near a person's spinal cord

Low Frequency Electric Stimulation Can Treat Back Pain: Study

a pink and purple micrograph of a longitudinal section of human spinal ganglion cells

Mouse Study Suggests Fibromyalgia Has Autoimmune Roots

Pain Researcher Quits Academia, Takes Lab Home with Him

mitochondrial transfer mitochondria inflammation pain

Macrophages in Mice Shuttle Mitochondria to Neurons in Need

mouse foot 28 days post chikungunya infection

Image of the Day: Viral Residue

schwann cells

Special Schwann Cells in Mice Play Unsung Role in Pain

Men React to Repeated Painful Experiences Differently than Women Do

Synthetic Botox Treats Chronic Pain in Mice

Contributors

Prizes and Penalties

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Photo of a woman with straight dark hair looking fatigued lying in bed with a grey blanket covering her.

Immune Markers Help Identify Subgroups of ME/CFS Patients

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A watercolor illustration of the human brain.

New Neurons Continue to Form in Adult Human Brains

Image of salmon and tuna nigiri as well as California rolls arranged on a circular black plate.

Engineered Bacteria Detox Mercury from a Fish-Rich Diet

Multimedia

A large number of stylized antibodies

The Holy Grail Hunt in De Novo Antibody Design

Twist Bio 
Conceptual 3D image of a multicolored membrane protein on a black background.

Making the Most of Membrane Protein Production

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July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

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An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

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Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

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Products

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Introducing the iQue 5 HTS Platform: Empowering Scientists  with Unbeatable Speed and Flexibility for High Throughput Screening by Cytometry

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Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

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Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery

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BRANDTECH Scientific Launches New Website for VACUU·LAN® Lab Vacuum Systems