Synthetic Botox Treats Chronic Pain in Mice
Abby Olena | Jul 18, 2018
Researchers silence pain neurons in the mouse spinal cord with injections of botulinum toxins modified to bind to the neurons’ receptors.
Men React to Repeated Painful Experiences Differently than Women Do
Men React to Repeated Painful Experiences Differently than Women Do
Men’s pain tolerance decreases when exposed to a setting where they’ve previously had a painful experience.
Men’s pain tolerance decreases when exposed to a setting where they’ve previously had a painful experience.
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Targeting Sodium Channels for Pain Relief
Catherine Offord | Jan 1, 2018
The race to develop analgesic drugs that inhibit sodium channel NaV1.7 is revealing a complex sensory role for the protein.
Prizes and Penalties
Bob Grant | Jan 1, 2018
Life is filled with pleasure and pain. Science and society are struggling mightily with both.
Contributors
Jef Akst and Katarina Zimmer | Jan 1, 2018
Meet some of the people featured in the January 2018 issue of The Scientist.
Infographic: Two Pain Paths Diverge in the Body
Mark R. Hutchinson | Dec 31, 2017
The acute pain that results from injury or disease is very different from chronic pain.
Infographic: A Painful Pathway
Catherine Offord | Dec 31, 2017
Since the mid-2000s, the voltage-gated sodium channel NaV1.7 has emerged as a promising target for a new class of analgesics.
Painful Realities
The Scientist Staff | Dec 31, 2017
Dave Thomas, a researcher at the National Institute on Drug Abuse, talks about the harsh truths and frustrating complexity of pain and analgesia.
Optogenetic Therapies Move Closer to Clinical Use
Shawna Williams | Nov 16, 2017
With a clinical trial underway to restore vision optogenetically, researchers also see promise in using the technique to treat deafness, pain, and other conditions.