Tiled blue-gray MRI readouts of a human brain.
Cancer Tied to Reduced Risk of Alzheimer’s Disease
Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.
ABOVE: © ISTOCK.COM, HAYDENBIRD
Cancer Tied to Reduced Risk of Alzheimer’s Disease
Cancer Tied to Reduced Risk of Alzheimer’s Disease

Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.

Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.

ABOVE: © ISTOCK.COM, HAYDENBIRD

dementia

A model of a brain made of many stacked, thin layers of brightly-colored material.
Neurons Damaged in Dementia Recognize Interruptions to Patterns
Anna Napolitano | Mar 16, 2022
A new study reveals a network of neurons that, when disrupted, impairs adaptation to new circumstances in several types of dementia.
illustration of brain cells in blue with amyloid plaques in orange and pink immune cells
Excerpt from The Memory Thief
Lauren Aguirre | Jun 1, 2021
Author Lauren Aguirre finds reasons for optimism in the fight against Alzheimer’s disease.
Dietary Spermidine Boosts Cognition in Insects and Rodents
Ruth Williams | Apr 15, 2021
Mice and flies given the polyamine in their diet have increased brain cell metabolism and cognitive function, and epidemiological data hints at a similar benefit in humans.
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
a patient getting blood drawn for testing
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
Shawna Williams | Nov 2, 2020
The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.
Poor Sleep Linked with Future Amyloid-β Build Up
Abby Olena | Sep 11, 2020
Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.
Alzheimer’s Gene Linked to Higher Risk of Severe COVID-19
Jef Akst | May 26, 2020
Two copies of the APOE4 variant, which confers a higher risk of dementia, doubles the risk of severe symptoms as a result of infection with SARS-CoV-2, according to a study.
Early Detection of Dementia with Smart Devices
Rachael Moeller Gorman | May 1, 2020
Digital biomarkers of cognitive decline could alert us to the early stages of dementia before irreversible damage occurs.
APOE Mutation Linked to Protection From Alzheimer’s: Case Study
Catherine Offord | Nov 5, 2019
A woman whose DNA suggested she’d develop early-onset dementia staved off cognitive decline for decades.
Image of the Day: Tau Aggregation
Emily Makowski | Oct 17, 2019
Endolysosome leakiness allows tau to build up in cells.
human macrophage
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
New Map Shows Brain Changes Associated with Alzheimer’s
Catherine Offord | Feb 4, 2019
The protein expression data, which are freely available online, could help identify new drug targets for the disease.
Alzheimer’s Drug Slows Symptoms, Reduces Plaques
Kerry Grens | Jul 26, 2018
In a clinical trial, patients on the highest injected dose had 30 percent less cognitive decline over time than people on a placebo.
Brain Prize Laureate Will Donate Some Winnings to Anti-Brexit Group
Shawna Williams | Mar 6, 2018
Alzheimer’s researcher John Hardy calls the departure “an unmitigated disaster” for science and healthcare in Britain.
Equivocal Findings of Alzheimer’s Trial Using Young Blood
Catherine Offord | Nov 5, 2017
A team of Stanford University researchers say that administering young people’s blood plasma to Alzheimer’s patients could improve cognitive function, but the results have been criticized.
Recovering Lost Memories
Jef Akst | Mar 21, 2016
Researchers use optogenetics to induce recall in an Alzheimer’s mouse model, suggesting the disease may not destroy memories permanently.
Opinion: The Present and Future of Neurogenomics
Joseph J. Higgins | Jun 13, 2013
Support the BRAIN Initiative, but don’t overlook the neurogenomic diagnostics that are already driving breakthroughs in brain and rare neurological disorders.
Non-coding Repeats Cause Peptide Clumps
Ruth Williams | Feb 7, 2013
Protein aggregates in the brains of some people with dementia or motor neuron disease have a surprising origin.
Junior Seau Had Brain Trauma
Beth Marie Mole | Jan 10, 2013
An NIH study finds that the former NFL linebacker who committed suicide last May had signs of degenerative brain disease.