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Illustration of light blue neurons with white amyloid plaques accumulating on their axons.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial
New Alzheimer’s Drug Slows Cognitive Decline in Clinical Trial

The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.

The Biogen-developed treatment, called lecanemab, appears to have a more clear-cut effect on slowing the disease than the company’s previous Alzheimer’s drug, Aduhelm.

dementia
Woman holding a glass of water in one hand and pill in the other
Daily Multivitamin May Slow Cognitive Decline in Seniors
Andy Carstens | Sep 14, 2022 | 2 min read
Researchers caution that it’s too soon to recommend supplements based on the results of a new study.
Tiled blue-gray MRI readouts of a human brain.
Cancer Tied to Reduced Risk of Alzheimer’s Disease
Dan Robitzski | Apr 14, 2022 | 7 min read
Observational evidence for the connection is solidifying, and some clues are emerging about the mechanisms that may explain it.
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | 4 min read
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
A model of a brain made of many stacked, thin layers of brightly-colored material.
Neurons Damaged in Dementia Recognize Interruptions to Patterns
Anna Napolitano | Mar 16, 2022 | 4 min read
A new study reveals a network of neurons that, when disrupted, impairs adaptation to new circumstances in several types of dementia.
illustration of brain cells in blue with amyloid plaques in orange and pink immune cells
Excerpt from The Memory Thief
Lauren Aguirre | Jun 1, 2021 | 10+ min read
Author Lauren Aguirre finds reasons for optimism in the fight against Alzheimer’s disease.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
Dietary Spermidine Boosts Cognition in Insects and Rodents
Ruth Williams | Apr 15, 2021 | 3 min read
Mice and flies given the polyamine in their diet have increased brain cell metabolism and cognitive function, and epidemiological data hints at a similar benefit in humans.
Eli Lilly Claims New Drug Can Slow Alzheimer’s-Related Decline
Lisa Winter | Mar 16, 2021 | 2 min read
Patients who received the drug fared better cognitively and functionally than those taking placebo, but still experienced losses in performance.
A Rising Star Launches Brain Power into Outer Space
Science Philosophy in a Flash - A Rising Star Launches Brain Power into Outer Space
Iris Kulbatski, PhD | 1 min read
Alysson Muotri shares how tapping into his inner creative spark fuels his pursuit of science.
a patient getting blood drawn for testing
First Alzheimer’s Blood Test Rolled Out for Clinical Use in US
Shawna Williams | Nov 2, 2020 | 4 min read
The test will be a cheaper and more accessible alternative to currently available diagnostic tools, researchers say.
Poor Sleep Linked with Future Amyloid-β Build Up
Abby Olena, PhD | Sep 11, 2020 | 3 min read
Accumulation of the protein was more likely to be found in the brains of people who slept less well years earlier, according to a new study.
Alzheimer’s Gene Linked to Higher Risk of Severe COVID-19
Jef Akst | May 26, 2020 | 2 min read
Two copies of the APOE4 variant, which confers a higher risk of dementia, doubles the risk of severe symptoms as a result of infection with SARS-CoV-2, according to a study.
Early Detection of Dementia with Smart Devices
Rachael Moeller Gorman | May 1, 2020 | 10+ min read
Digital biomarkers of cognitive decline could alert us to the early stages of dementia before irreversible damage occurs.
APOE Mutation Linked to Protection From Alzheimer’s: Case Study
Catherine Offord | Nov 5, 2019 | 2 min read
A woman whose DNA suggested she’d develop early-onset dementia staved off cognitive decline for decades.
Image of the Day: Tau Aggregation
Emily Makowski | Oct 17, 2019 | 1 min read
Endolysosome leakiness allows tau to build up in cells.
human macrophage
Image of the Day: Alzheimer’s Genes
Nicoletta Lanese | Aug 19, 2019 | 1 min read
Mutations within the MS4A gene cluster have been linked to changes in protein levels that affect disease risk.
New Map Shows Brain Changes Associated with Alzheimer’s
Catherine Offord | Feb 4, 2019 | 2 min read
The protein expression data, which are freely available online, could help identify new drug targets for the disease.
Alzheimer’s Drug Slows Symptoms, Reduces Plaques
Kerry Grens | Jul 26, 2018 | 2 min read
In a clinical trial, patients on the highest injected dose had 30 percent less cognitive decline over time than people on a placebo.
Brain Prize Laureate Will Donate Some Winnings to Anti-Brexit Group
Shawna Williams | Mar 6, 2018 | 1 min read
Alzheimer’s researcher John Hardy calls the departure “an unmitigated disaster” for science and healthcare in Britain.
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