A photo of a triple-negative breast cancer cell
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.
ABOVE: National Cancer Institute, University of Pittsburgh Cancer Institute
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice
A Fasting-Mimicking Diet Thwarts Breast Cancer in Mice

Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.

Coupling a diet low in calories, sugar, and protein with existing cancer drugs treats triple-negative breast cancer in mice, and low blood glucose is associated with better cancer outcomes in human patients.

ABOVE: National Cancer Institute, University of Pittsburgh Cancer Institute

dietary restriction

illustration of inside of human chest with highlighted gland between the lungs
Genetically Altered Mice Harness Benefits of Calorie Restriction  
Sophie Fessl | Feb 11, 2022
A study identifies a gene that appears to be partially responsible for the health effects of a limited diet.
Artist's impression of the human microbiome
Diet Implicated in Autism-Microbiome Link
Ruth Williams | Nov 11, 2021
The unbalanced gut flora present in some people with autism is not a driver of the condition but rather a consequence of eating behaviors characteristic of the condition, a new study claims.
Could Grandpa’s Early Diet Affect Your Health?
Shawna Williams | Apr 1, 2019
A large study seeks to answer whether a man’s childhood diet has transgenerational repercussions.
Researchers Explore the Genetics of Eating Disorders
Amy Lewis | Jan 1, 2019
Large-scale genomic studies of anorexia and bulimia are turning up clues about the conditions’ development and persistence.
Caloric Restriction Slows Signs of Aging in Humans
Diana Kwon | Mar 26, 2018
Findings from a randomized, controlled trial finds that reducing food intake decreases metabolism and reduces oxidative damage to tissues and cells.
Mitochondrial Networks Explain Why Caloric Restriction Extends Worms’ Lives
Jef Akst | Nov 7, 2017
Maintaining dynamic connections among the body’s mitochondria is required for the health and life-extending benefits of low-calorie diets for nematodes.
Study: Eating Less Helps Worms Learn
Aggie Mika | Aug 2, 2017
Food restriction decreases a metabolite that impedes associative learning in worms. 
Running on Empty
Bob Grant | Jun 1, 2017
Regularly taking breaks from eating—for hours or days—can trigger changes both expected, such as in metabolic dynamics and inflammation, and surprising, as in immune system function and cancer progression.
Growth Hormone Guidance
Jenny Rood | Mar 1, 2015
Intact growth hormone signaling pathways are needed for methionine restriction to extend mouse lifespan.