Parkinson’s Disease Enzyme Implicated in More Cases Than Realized
Parkinson’s Disease Enzyme Implicated in More Cases Than Realized

Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected.

Parkinson’s Disease Enzyme Implicated in More Cases Than Realized
Parkinson’s Disease Enzyme Implicated in More Cases Than Realized

Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected.

Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected.

dopamine
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Diana Kwon | Jul 31, 2018
Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.
Neuropharmacologist Arvid Carlsson Dies at 95
Neuropharmacologist Arvid Carlsson Dies at 95
Sukanya Charuchandra | Jul 2, 2018
The Nobel laureate’s discoveries led to a treatment for Parkinson’s disease.
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
Deep Brain Stimulation Boosts Insulin Sensitivity
Deep Brain Stimulation Boosts Insulin Sensitivity
Shawna Williams | May 24, 2018
One patient with diabetes was able to reduce his medication use while receiving targeted electrical pulses.
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Abby Olena | Aug 30, 2017
Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.
Reprogrammed Glia Improve Symptoms in a Mouse Model of Parkinson’s
Reprogrammed Glia Improve Symptoms in a Mouse Model of Parkinson’s
Diana Kwon | Apr 10, 2017
By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.
Neural Activity Reflects a Bird’s Perception of How Well It Sings
Neural Activity Reflects a Bird’s Perception of How Well It Sings
Catherine Offord | Mar 1, 2017
Zebra finches dial down dopamine signaling when they hear errors in a song performance.
Infographic: Taking Note of Singing Errors
Infographic: Taking Note of Singing Errors
Catherine Offord | Feb 28, 2017
Birds' brains respond to distorted songs with changes in dopamine signaling.
Why Obese Mice Prefer To Sit Around All Day
Why Obese Mice Prefer To Sit Around All Day
Joshua A. Krisch | Jan 3, 2017
A study links excess body weight in the rodents with dopamine receptor inactivity and reduced movement.