Giannina Descalzi
Giannina Descalzi Studies the Factors Underlying Chronic Pain
The University of Guelph neuroscientist is scoping out the brain regions and genes that change as a consequence of pain that lasts for months or even years.
ABOVE: University of Guelph
Giannina Descalzi Studies the Factors Underlying Chronic Pain
Giannina Descalzi Studies the Factors Underlying Chronic Pain

The University of Guelph neuroscientist is scoping out the brain regions and genes that change as a consequence of pain that lasts for months or even years.

The University of Guelph neuroscientist is scoping out the brain regions and genes that change as a consequence of pain that lasts for months or even years.

ABOVE: University of Guelph

dopamine

A pink and blue illustration of the central nervous system, visible through a translucent outline of a human head and shoulders, zooms in to show an illustration of interconnected neurons
Specific Brain Cells Linked to Parkinson’s Disease
Dan Robitzski | May 6, 2022
Research identifies 10 types of dopamine-making neurons, one of which seems to die off during the disease.
Bee on purple flower
Dopamine Drives Bee Desires: Study
Natalia Mesa | Apr 28, 2022
Like in humans, the neurotransmitter appears to play a role in generating wanting-like behavior and, perhaps, happy memories in honeybees.
disease & medicine, neuroscience, microelectrode, techniques, dopamine, serotonin, neuromodulator, neurotransmitter, neuropsychiatric disorders
Serotonin and Dopamine Linked to Decision-Making: Study
Amanda Heidt | Oct 16, 2020
In a first-of-its-kind study, researchers monitored subsecond changes in levels of the neurotransmitters in the human brain, unlocking new insight into their function.
pharmacology medicine parkinson's disease dopamine l-dopa levodopa Hornykiewicz obituary
Oleh Hornykiewicz, Who Pioneered Treatment for Parkinson’s, Dies
Amanda Heidt | Jun 18, 2020
The University of Toronto and University of Vienna pharmacologist developed L-dopa, a precursor to dopamine that remains the most widely used therapy for Parkinson’s disease.
Neurobiologist Paul Greengard Dies
Ashley Yeager | Apr 15, 2019
The Nobel laureate revolutionized our understanding of how brain cells communicate.
Parkinson’s Patient Transplanted with Neurons Derived from iPSCs
Ashley P. Taylor | Nov 14, 2018
This is the first time researchers have tested the use of the reprogrammed stem cells in the human brain.
Robb Rutledge Pinpoints the Factors That Make Us Happy—Or Not
Shawna Williams | Nov 1, 2018
The University College London researcher is a pioneer in the use of smartphone apps for psychology research.
Nicotine’s Effects Passed On Through Generations of Mice
Kerry Grens | Oct 16, 2018
Male rodents exposed to nicotine had changes in sperm genome methylation and produced pups and grandpups with abnormal behavior.
Maternal Obesity and Diabetes Linked to Autism in Children
Sukanya Charuchandra | Oct 1, 2018
Inflammation may be a strong contender for the connection between mom’s weight and children’s neurodevelopment, according to lab studies on animals.
Image of the Day: Dopamine Made Them Do It
Sukanya Charuchandra | Sep 28, 2018
Levels of the neurotransmitter drive ant foraging behavior in the desert.
Parkinson’s Disease Enzyme Implicated in More Cases Than Realized
Sukanya Charuchandra | Aug 2, 2018

Levels of active LRRK2 were high even in Parkinson’s patients without a mutation in LRRK2, suggesting that inhibitors of the protein could treat a wider patient population than expected.

Lindsay Hanford, Geoff B Hall
Trial Launched to Treat Parkinson’s with Reprogrammed Stem Cells
Diana Kwon | Jul 31, 2018
Surgeons will inject approximately 5 million dopamine-producing progenitor cells into patients’ brains.
Neuropharmacologist Arvid Carlsson Dies at 95
Sukanya Charuchandra | Jul 2, 2018
The Nobel laureate’s discoveries led to a treatment for Parkinson’s disease.
Dopamine Neuron Implants Ease Parkinson’s Symptoms in Monkeys
Sukanya Charuchandra | Jun 20, 2018
The stem cell–derived transplants were stable for 24 months and led to wide-ranging behavioral improvements in the monkeys.  
Deep Brain Stimulation Boosts Insulin Sensitivity
Shawna Williams | May 24, 2018
One patient with diabetes was able to reduce his medication use while receiving targeted electrical pulses.
Parkinson’s Disease Cell Therapy Relieves Symptoms in Monkeys
Abby Olena | Aug 30, 2017
Neurons derived from human induced pluripotent stem cells fill in for lost dopamine neurons in a primate model of the disease.
Reprogrammed Glia Improve Symptoms in a Mouse Model of Parkinson’s
Diana Kwon | Apr 10, 2017
By converting glial cells into dopaminergic neurons, scientists were able to partially rescue motor behavior in mice.
Neural Activity Reflects a Bird’s Perception of How Well It Sings
Catherine Offord | Mar 1, 2017
Zebra finches dial down dopamine signaling when they hear errors in a song performance.
Infographic: Taking Note of Singing Errors
Catherine Offord | Feb 28, 2017
Birds' brains respond to distorted songs with changes in dopamine signaling.