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Scientists Destroy Entire Chromosome with CRISPR
Kerry Grens | Aug 1, 2017
Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.
More Mini Brains
Jef Akst | Feb 17, 2016
Simple versions of brain organoids could serve as new models for testing the effects of drugs, researchers reported at this year’s AAAS meeting.
Probing Down Syndrome with Mini Brains
Bob Grant | Oct 20, 2015
Researchers create cerebral organoids using induced pluripotent stem cells from patient skin cells and characterize protein-expression changes linked to cognitive impairment.
Week in Review: April 14–18
Tracy Vence | Apr 18, 2014
Genome-wide effects of trisomy 21; RNA-based signs of transgenerational stress; depression and resilience; a call to overhaul US biomedical research system
Trisomy 21 Effects Seen Genome-wide
Rina Shaikh-Lesko | Apr 16, 2014
The extra chromosome behind Down’s syndrome can impact transcriptional regulation beyond chromosome 21, a study finds.
Should Standard Prenatal Screening be Scrapped?
Bob Grant | Feb 28, 2014
Researchers suggest that a new prenatal DNA test should become the new standard to detect Down syndrome in fetuses.
New Down Syndrome Protein Found
Edyta Zielinska | Mar 26, 2013
Researchers identify a protein involved in the chromosomal disorder that could explain its characteristic learning deficits.
Year of the Fetus
Beth Marie Mole | Dec 18, 2012
2012 saw the birth of a handful of non-invasive genetic prenatal tests, but the young industry faces growing pains as legal and ethical questions loom.
Patent War for Prenatal Tests
Cristina Luiggi | Jun 28, 2012
Four companies who have developed noninvasive genetic prenatal tests are fighting over who has the patent rights to the new and revolutionary techniques.
Mom's Blood Reveals Baby's Down Syndrome
Jef Akst | Oct 25, 2011
Last week researchers released the first non-invasive prenatal test for Down syndrome, and more such tests are expected in the coming months.