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Closeup of a pair of hands in blue gloves holding a white mouse and injecting it with an amber colored liquid.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.
Opioids Recruit the Immune System to Cause Withdrawal Symptoms
Opioids Recruit the Immune System to Cause Withdrawal Symptoms

A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.

A study finds that T cells induced by heroin cross the blood-brain barrier to wreak havoc on the brain, hinting at new ways to prevent withdrawal.

drugs
Artist’s rendition of neural connections, with inactive neurons in the background
Ketamine Flips a “Switch” in Mice’s Brain Circuitry: Study
Andy Carstens | Dec 9, 2022 | 6 min read
After injecting moderate doses of the dissociative anesthetic into the animals, previously “awake” brain cells go dark, and those that had been dormant suddenly light up.
a man collects water using a fishing pole and can
World’s Rivers Rife with Drugs: Study
Christie Wilcox, PhD | Feb 15, 2022 | 2 min read
Levels of pharmaceuticals considered unsafe for aquatic organisms were found at more than one-quarter of sampling sites.
Fish in a big blue aquarium
Microbes Responsible for Stealing Aquarium Medicine
Amanda Heidt | Feb 1, 2022 | 6 min read
Researchers discover that bacteria break down medicinal compounds for their nitrogen, solving a mystery that has vexed aquatic veterinarians for years.
a brown trout in the hands of a person wearing a green jacket
Trout Appear to Get Hooked on Meth
Christie Wilcox, PhD | Jul 6, 2021 | 5 min read
After eight weeks of exposure to ecologically plausible levels of methamphetamines, the fish tended to prefer meth-laced water over water without the drug.
ancient cannabis evidence THC china burial site ritual ceremony pot brazier
Ancient Wooden Pots from China Contain Cannabis Residue
Chia-Yi Hou | Jun 12, 2019 | 2 min read
A brazier and charred stones, thought to be part of burial ceremonies, preserve signs that people used the drug thousands of years ago.
Image of the Day: Mind Altering
Carolyn Wilke | Mar 11, 2019 | 1 min read
A study in rats finds that tiny doses of the psychedelic drug DMT may yield positive effects for anxiety and depression, but there could be downsides too.
The UK Pharmaceutical Industry Braces for Brexit
Diana Kwon | Oct 12, 2018 | 9 min read
As Britain’s departure date from the European Union approaches, drugmakers are preparing for potential changes to regulatory procedures and border controls.
Synthetic Cannabinoid K2 Overdoses Are Rampant. Here’s Why.
Ashley Yeager | Aug 17, 2018 | 5 min read
NIDA pharmacologist Michael Baumann explains how “unscrupulous vendors” hijacked compounds used in neuroscience and turned them into dangerous drugs.
More Vaccinations, Experimental Drugs as Potential Ebola Contacts Rise
Sukanya Charuchandra | May 30, 2018 | 2 min read
The World Health Organization predicts the number of cases in Democratic Republic of Congo will rise up to 300 by July.  
New Treatments for Phenylketonuria Aim to Loosen Reins on Strict Diet
Diana Kwon | May 29, 2018 | 5 min read
Biotechs have developed enzyme replacements and genetically modified probiotics to treat patients with the rare metabolic disorder.
FDA Approves Drug to Ease Symptoms of Opioid Withdrawal
Catherine Offord | May 17, 2018 | 1 min read
Lucemyra is the first non-opioid drug to be approved in the U.S. specifically for this purpose.
Research Scandal Involving Popular Heart Drug Engulfs Three More Papers
Alison McCook, Retraction Watch | May 4, 2018 | 3 min read
The scientists involved have hired lawyers to fight the conclusions of a recent investigation into some studies of Diovan in Japan.
Researchers Getting Smarter About Pairing Cancer Treatments
Anna Azvolinsky | Apr 1, 2018 | 10+ min read
Multidrug combinations lead to better results for cancer patients, but efficiently identifying them is proving difficult.
Sanofi and Celgene Spend $20 Billion in Major Biotech Acquisitions
Katarina Zimmer | Jan 22, 2018 | 2 min read
Pharmaceutical giant Sanofi to take over hemophilia drugmaker Biovertiv, while Celgene will buy cancer drugmaker Juno Therapeutics.
New CAR T-Cell Therapy Shows Promise in Trial for Leukemia
Katarina Zimmer | Nov 21, 2017 | 2 min read
The immunotherapy, which targets CD22 on cancer cells rather than CD19, might prove useful in patients for whom previous T-cell treatments were unsuccessful. 
European Medicines Agency to Move to Amsterdam
Shawna Williams | Nov 20, 2017 | 1 min read
A coin toss decides the agency’s post-Brexit home once it departs from London.
Puerto Rico’s Hurricane Damage May Mean Drug Shortages
Ashley P. Taylor | Oct 11, 2017 | 2 min read
Three weeks after Hurricane Maria hit the island, pharmaceutical plants are not back up to speed.
Image of the Day: Better Together
The Scientist Staff and The Scientist Staff | Oct 5, 2017 | 1 min read
When it comes to thwarting roundworms, scientists find that combining four antiparasitic drugs in smaller doses packs a greater punch than the four drugs alone.
Doctors’ Advice to Finish Antibiotics Overlooks Resistance
Abby Olena, PhD | Aug 11, 2017 | 4 min read
There is little evidence that full treatment durations discourage the development of drug-resistant bacteria.
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