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Chromosome with gold band
Immunity Genes May Play a Role in Down Syndrome
Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.
Immunity Genes May Play a Role in Down Syndrome
Immunity Genes May Play a Role in Down Syndrome

Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.

Extra copies of four interferon receptor genes found on human chromosome 21 trigger developmental changes in a mouse model of Down syndrome.

embryology

Fluorescent microscopy image of an embryo model representing four tissue layers of this developmental stage. Cyan-labeled cells are clustered at the top of an ovoid structure, underneath them are yellow-labeled cells and under them red-labeled cells, and surrounding all three layers are white labeled cells.
The First Human Embryo Model From Embryonic Stem Cells
Shelby Bradford, PhD | Mar 1, 2024 | 2 min read
Jacob Hanna developed a method for replicating embryogenesis outside of the uterus to understand the underlying mechanisms.
microscope image series showing synthetic embryo development
Mouse Embryo: No Sperm, Egg, or Uterus Required
Christie Wilcox, PhD | Aug 2, 2022 | 3 min read
Using stem cells and a bioreactor, researchers generated living embryos that survived for more than a week and began to develop internal organs.
Multiple purple and pink renditions of stem cells appear as spherical clusters enveloped in translucent bubbles
Mammalian Embryos Might Not Need Primitive Streaks After All
Dan Robitzski | Dec 2, 2021 | 7 min read
The primitive streak, a structure that emerges during mammalian and avian gastrulation, might be a byproduct rather than a landmark of the embryonic development process.
lewis wolpert obituary developmental biology embryo 14 day rule
High Profile Developmental Biologist Lewis Wolpert Dies at 91
Shawna Williams | Feb 16, 2021 | 2 min read
Wolpert, who conducted research at University College London, was known for his work on morphogenesis and pattern development in embryos and for his multiple books and broadcast appearances.
These Molecules Zipper Embryos Closed
Ashley Yeager | Aug 1, 2018 | 2 min read
Actin rings seal off the ball of cells, aiding in implantation in the uterus. But faults in the process could explain why some pregnancies fail.
Infographic: Embryonic Zippering
Ashley Yeager | Jul 31, 2018 | 1 min read
How actin seals embryos early in development
Animals’ Embryonic Organizer Now Discovered in Human Cells
Jim Daley | May 23, 2018 | 4 min read
The finding confirms that a cluster of cells that directs the fate of other cells in the developing embryo is evolutionarily conserved across the animal kingdom.
Passing the Torch
Mary Beth Aberlin | Dec 1, 2017 | 3 min read
Looking back, looking forward
Image of the Day: Brand New Pyjamas
The Scientist | Aug 23, 2017 | 1 min read
As it matures, this chromatophore-clad pyjama squid (Sepioloidea lineolata) hatchling will learn to use the color-changing cells that adorn its body to alter its appearance.
Image of the Day: Embryonic Ripples
The Scientist | Jul 26, 2017 | 1 min read
This fluttering clump of colorful cells is a zebrafish embryo, visualized by many stacked images.
Embryonic Evolution Through Ernst Haeckel’s Eyes
Diana Kwon | May 1, 2017 | 2 min read
The 19th century biologist’s drawings, tainted by scandal, helped bolster, then later dismiss, his biogenetic law.
Famed Mammalian Embryologist Dies
Jef Akst | Dec 1, 2016 | 2 min read
Andrzej Tarkowski’s research laid the groundwork for future advances in cloning, stem cell research, and in vitro fertilization.
Study: IVF Media Affects Treatment Outcomes
Ben Andrew Henry | Aug 24, 2016 | 1 min read
Differences between cultures used for in vitro fertilization techniques can impact fertility and offspring health, researchers report.
Notable Science Quotes
The Scientist | Jun 1, 2016 | 2 min read
14-day-old embryos, prioritizing biodiversity, and more
Organelle Architecture
Mary Beth Aberlin | Dec 1, 2013 | 3 min read
There’s beauty in a cell’s marriage of structure and function.
Seeing Clearly
Jef Akst | Apr 1, 2013 | 1 min read
Zebrafish are showing the way to new insights in cancer research.
Go Forth, Cells
Dan Cossins | Jan 31, 2013 | 1 min read
Watch the cell transplant experiments in zebrafish that suggest certain embryonic cells rely on intrinsic directional cues for collective migration.
Contributors
Beth Marie Mole | Nov 1, 2012 | 3 min read
Meet some of the people featured in the November 2012 issue of The Scientist.
Long and Rocky Roads
Mary Beth Aberlin | Nov 1, 2012 | 3 min read
From basic research to beneficial therapies
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