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p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
p53 Unleashes Endogenous Retroviruses to Tackle Tumors: Study
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
New experiments suggest the famous tumor-suppressing protein uses viral elements lingering in the genome to get cancerous cells to announce their presence to the immune system.
endogenous retrovirus
Infographic: Human Endogenous Retroviruses and Disease
Katarina Zimmer | Jan 1, 2019 | 3 min read
Human endogenous retroviruses that colonized vertebrate DNA millions of years ago have long been dismissed as junk DNA, but researchers now know that they may play important roles in cancer, neurodegeneration, and other ailments.
Jumping Genes Inactivated with CRISPR in Pigs
Shawna Williams | Aug 10, 2017 | 2 min read
The study could pave the way for transplanting porcine organs to humans without the risk of reigniting endogenous retroviruses.
Viral Protein Boosts Muscle Mass in Male Mice
Jef Akst | Sep 14, 2016 | 2 min read
An endogenous retrovirus that supports placenta formation in females also helps male mice build muscle, according to a study.
Viral Remnants Help Regulate Human Immunity
Jyoti Madhusoodanan | Mar 3, 2016 | 3 min read
Endogenous retroviruses in the human genome can regulate genes involved in innate immune responses.
Modified Pigs as Organ Donors?
Karen Zusi | Oct 9, 2015 | 1 min read
Researchers have edited more than 60 genes in pig embryos to facilitate organ donations for humans.
Endogenous Retrovirus Active in ALS
Jef Akst | Sep 30, 2015 | 3 min read
Researchers uncover evidence that a retrovirus embedded within the human genome may play a role in the pathology of amyotrophic lateral sclerosis.