Enhancers
Finding Enhancers with CRISPR
Finding Enhancers with CRISPR
Anna Azvolinsky | Jan 11, 2016
Researchers use CRISPR/Cas9 to screen for noncoding elements in the human genome.
Silencing Surprise
Silencing Surprise
Jenny Rood | Jun 1, 2015
A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.
Bigger Brains
Bigger Brains
Jenny Rood | Feb 20, 2015
Researchers identify a human DNA element that spurs neurogenesis and brain growth when placed in mice.
DNA Loop-the-Loops
DNA Loop-the-Loops
Kate Yandell | Dec 11, 2014
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Enhanced Enhancers
Enhanced Enhancers
Eric Olson | Nov 1, 2014
The recent discovery of super-enhancers may offer new drug targets for a range of diseases.
Exploring the Roles of Enhancer RNAs
Exploring the Roles of Enhancer RNAs
Ashley P. Taylor | May 7, 2014
Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.
Enhancer and Promoter Atlases
Enhancer and Promoter Atlases
Ashley P. Taylor | Mar 26, 2014
Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.
About Face
About Face
Abby Olena | Oct 25, 2013
Researchers show that genetic enhancer elements likely contribute to face shape in mice.