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Finding Enhancers with CRISPR
Anna Azvolinsky | Jan 11, 2016
Researchers use CRISPR/Cas9 to screen for noncoding elements in the human genome.
Jenny Rood | May 31, 2015
A chromatin remodeler in embryonic stem cells clears the DNA for mRNA transcription while stifling the expression of noncoding transcripts.
Jenny Rood | Feb 20, 2015
Researchers identify a human DNA element that spurs neurogenesis and brain growth when placed in mice.
Kate Yandell | Dec 11, 2014
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Eric Olson | Oct 31, 2014
The recent discovery of super-enhancers may offer new drug targets for a range of diseases.
Exploring the Roles of Enhancer RNAs
Ashley P. Taylor | May 7, 2014
Scientists have recently discovered that enhancers are often transcribed into RNAs. But they’re still not sure what, if anything, these eRNAs do.
Enhancer and Promoter Atlases
Ashley P. Taylor | Mar 26, 2014
Consortium annotates the human genome with cell type-specific information about transcription start sites, active enhancers, and their expression throughout the body.
Abby Olena | Oct 25, 2013
Researchers show that genetic enhancer elements likely contribute to face shape in mice.