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Opinion: Splashing Cold Water on Poop Transplants for Weight Loss
Gut microbiome–based solutions hold promise for addressing obesity, but are they overhyped?
Opinion: Splashing Cold Water on Poop Transplants for Weight Loss
Opinion: Splashing Cold Water on Poop Transplants for Weight Loss

Gut microbiome–based solutions hold promise for addressing obesity, but are they overhyped?

Gut microbiome–based solutions hold promise for addressing obesity, but are they overhyped?

Fecal transplant
A section of a mouse distal colon showing luminal contents with bacteria in magenta, the mucus lining (green) and the epithelial cell barrier of the gut (blue, right).
Mapping the Neighborhoods of the Gut Microbiome
Abby Olena, PhD | Jul 1, 2022 | 7 min read
Researchers are going beyond fecal samples to understand how the patterns of commensal microbes in the gastrointestinal tract influence development and health.
Photo taken from the perspective of a lab worker in a white coat and purple gloves preparing multiple fecal transplant capsules at a time.
Banking Previous Poos: Could a Transplant of Feces from Your Past Heal You?
Dan Robitzski | Jun 30, 2022 | 9 min read
The Scientist spoke with Brigham and Women’s Hospital and Harvard Medical School researchers Scott Weiss and Yang-Yu Liu, who propose that people bank stool samples when they’re young and healthy so that they can be transplanted to rejuvenate the gut microbiome later on.
An abstract stained-glass portrait of a woman with an image of an eye representing the brain
Through the Looking Glass: Aging, Inflammation, and Gut Rejuvenation
Iris Kulbatski, PhD | 4 min read
Renewing the aging gut microbiome holds promise for preventing inflammatory brain and eye degeneration.
Artist’s rendition of bright blue microbes among intestinal lining
Study Links Depression with High Levels of an Amino Acid
Dan Robitzski | Jun 14, 2022 | 5 min read
Experiments in animals and observations in humans suggest that the amount of proline circulating in one’s plasma has a strong association with depression severity.
Artist's impression of the human microbiome
Diet Implicated in Autism-Microbiome Link
Ruth Williams | Nov 11, 2021 | 3 min read
The unbalanced gut flora present in some people with autism is not a driver of the condition but rather a consequence of eating behaviors characteristic of the condition, a new study claims.
A person holding a section of his face and looking in to his brain through a magnifying glass stock illustration
Science Philosophy in a Flash - A Look at Aging Through Young Eyes 
Iris Kulbatski, PhD | 1 min read
Aimée Parker shares how her childlike curiosity and collaborative spirit motivate her scientific pursuits.
A person wearing a purple glove holds out a blue pill
Fecal Microbiota Transplantation Is Poised for a Makeover
Shawna Williams | Jun 1, 2021 | 9 min read
With multiple microbiota therapeutics in the pipeline for recurrent Clostridium difficile infection, clinicians foresee a shift in treatment options for the condition.
an illustration of a mix of different bacteria
Fecal Transplant Could Boost Immunotherapy to Treat Melanoma
Shawna Williams | Feb 12, 2021 | 4 min read
The results from two Phase 1 trials bolster the case that the gut microbiome plays a role in response to the drugs.
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Fecal Transplant Restores Youth to Old Mice
Roni Dengler, PhD | 3 min read
Microbiota from young mice reversed some aspects of aging and enhanced brain health in aged mice.
Fecal Transfer from Moms to Babies After C-Section: Trial Results
Ruth Williams | Oct 1, 2020 | 4 min read
Tiny doses of maternal poo mixed with breast milk and given to Cesarean-born infants makes their gut microbiota resemble those of babies born vaginally.
Exercise Changes Our Gut Microbes, But How Isn’t Yet Clear
Ashley Yeager | Aug 15, 2019 | 5 min read
Physical activity, independent of diet, shifts the composition of bacteria in the intestines, spurring researchers to search for species that might provide benefits akin to working out.
Checking Checkpoints for Treating Cancer
The Scientist Creative Services Team | 1 min read
Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.
fmt fecal matter transplant microbiome c. difficile
Curious Cure: Human Waste
Kendall Powell | Aug 12, 2019 | 8 min read
Studies point to the life-saving record of fecal transplants for patients infected with C. diff, despite a recent death. Doctors are now testing the procedure for other conditions.
Does the Microbiome Help the Body Fight Cancer?
Catherine Offord | Jul 10, 2019 | 4 min read
Research in mice and humans is beginning to establish a link between the composition of microbes in the gut and immune responses to tumor cells, but the mechanisms are not yet clear.
fecal matter transplant FDA suspend halt clinical trials patient dies died antibiotic resistance drug resistant
FDA Suspends Clinical Trials Involving Fecal Transplants
Chia-Yi Hou | Jun 14, 2019 | 1 min read
The agency issued a safety warning after two patients contracted antibiotic-resistant infections and one of the patients died.
Fecal Transplants More Successful from “Super-Donors”
Shawna Williams | Jan 22, 2019 | 2 min read
A review finds that for several conditions, poop from certain healthy people is more likely to provide relief for recipients.
Fecal Transplant Heals Colitis Caused by Immunotherapy
Anna Azvolinsky | Nov 12, 2018 | 4 min read
A case study of two patients with advanced cancer shows it might be possible to avoid a common and severe side effect of immunotherapy treatment.
Stanley Falkow, Father of Molecular Microbial Pathogenesis, Dies
Catherine Offord | May 9, 2018 | 3 min read
The microbiologist was known for his work on bacterial antibiotic resistance and infectious disease.
a woman riding a mountain bike in the woods
Athletes’ Microbiomes Differ from Nonathletes
Jef Akst | Jun 1, 2017 | 4 min read
Researchers are beginning to uncover a link between activity level and the microbial makeup of one’s gut.
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