The future of personalized medicine could lie in a person’s own past. Given the influence gut microbes have over a wide variety of health conditions, researchers from Brigham and Women’s Hospital and Harvard Medical School have an unusual proposal: people could bank their poop when they’re young and in good health so that it can be transplanted back into their system when their health is waning.
The idea, proposed today (June 30) as a review in Trends in Molecular Medicine, comes from existing evidence on autologous fecal microbiota transplantation (FMT)—a fecal transplant of a person’s own stool. The researchers suggest that such FMTs could rejuvenate the microbiome later in life, and in doing so, may help prevent conditions ranging from obesity to asthma, though they’re careful to avoid saying that there’s definitive proof such a procedure would help.
The Scientist spoke with coauthors Yang-Yu Liu and Scott Weiss to learn ...