Histology of mouse lungs using purple and green staining on a white background. Left: a healthy lung. Right: a fibrotic lung.
Immunotherapy Treats Fibrosis in Mice
Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.
Immunotherapy Treats Fibrosis in Mice
Immunotherapy Treats Fibrosis in Mice

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

Researchers report that vaccination against proteins found on profibrotic cells reduced liver and lung fibrosis in laboratory rodents.

fibroblasts
A single neutrophil white blood cell in the artery with red blood cells floating around it
Missing Y Chromosome in Mouse Blood Causes Heart Dysfunction
Patience Asanga | Jul 16, 2022
An analysis of human data from the UK biobank also finds an association between Y chromosome loss and heart disease in men.
a skin-coated robot finger sits in a petri dish of culture media
Robot Finger’s Living Skin Stretches, Heals Like the Real Thing
Christie Wilcox | Jun 10, 2022
Researchers in Japan have given a plastic robot finger a layered coating made from actual, living skin cells. Next, they aim to add hair and sweat glands.
Understanding Immune-Mediated Damage After Respiratory Infection
The Scientist Creative Services Team in collaboration with 10x Genomics
Paul Thomas from St. Jude Children’s Research Hospital will discuss how he used single cell and spatial transcriptomics to discover the underlying mechanism of an inflammatory immune response in the lungs.
A close up shot of a thumb pointing to a pimple on a patch of bare skin
Skin Cells Can Transform To Help Fight Acne
Dan Robitzski | Mar 2, 2022
A new study reveals that the fibroblasts in tissue surrounding acne infections play an active role in the body’s immune response—and that existing treatments help trigger them to do so.
Scientific illustration of a migrating breast cancer cell.
Breast Cancer Cells Churn Out Cholesterol to Fuel Metastasis
Alejandra Manjarrez | Feb 4, 2022
A study uncovers a novel connection between the biomolecule and cancer progression.
knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl | Jan 6, 2022
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
cardiac fibrosis car t chimeric antigen receptor immunotherapy t cells fibroblasts cardiovascular disease
CAR T Immunotherapy May Find New Use in Treating Cardiac Fibrosis
Emma Yasinski | Sep 11, 2019
Scientists show the approach can kill cells that cause hardening of heart tissue in mice.
Image of the Day: Scarred Hearts
Ashley Yeager | Dec 4, 2018
Maps of diving cells before and after heart attacks in mice offer additional evidence against the existence of cardiac stem cells.
Image of the Day: Cooking Up Neurons
The Scientist Staff and The Scientist Staff | May 11, 2018
Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.
Image of the Day: 3-D Nanofibers
The Scientist Staff and The Scientist Staff | Mar 7, 2018
Researchers created a nanofibrous scaffold to see how it supports cell growth.
Image of the Day: Itty Bitty Cell Sucker
The Scientist Staff | Jul 21, 2017
With a diameter smaller than 100 nanometers, this nanopipette’s indiscernible tip is tiny enough to suck up minute contents of a single cell. 
With CRISPR, Scientists Make Neurons From Fibroblasts
Kerry Grens | Aug 15, 2016
Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.
Watching Cancer on the Move
Jef Akst | Dec 15, 2015
Fibroblasts help tumors metastasize by paving a “migration highway” through the extracellular matrix, scientists report.
Highly Cited Stem Cell Paper Pulled
Kerry Grens | Aug 5, 2014
The authors of a 2008 Nature paper have retracted it after new data watered down the conclusions.
Week in Review: February 24–28
Tracy Vence | Feb 28, 2014
New PLOS data sharing rules; mouse cortical connectome published; reprogramming astrocytes into neurons and fibroblasts into hepatocytes
A Hair-Raising Solution?
Dan Cossins | Sep 1, 2013
In the long-fought battle against baldness, researchers are finally identifying molecular pathways that can be manipulated to generate new hair follicles.
We're All Connected
Mary Beth Aberlin | May 1, 2013
A look at some of biology’s communication networks
The Science of Stretch
Helene M. Langevin | May 1, 2013
The study of connective tissue is shedding light on pain and providing new explanations for alternative medicine.