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A single neutrophil white blood cell in the artery with red blood cells floating around it

Missing Y Chromosome in Mouse Blood Causes Heart Dysfunction

Patience Asanga | Jul 16, 2022 | 3 min read

An analysis of human data from the UK biobank also finds an association between Y chromosome loss and heart disease in men.

a skin-coated robot finger sits in a petri dish of culture media

Robot Finger’s Living Skin Stretches, Heals Like the Real Thing

Christie Wilcox, PhD | Jun 10, 2022 | 2 min read

Researchers in Japan have given a plastic robot finger a layered coating made from actual, living skin cells. Next, they aim to add hair and sweat glands.

Understanding Immune-Mediated Damage After Respiratory Infection

The Scientist Creative Services Team in collaboration with 10x Genomics | 1 min read

Paul Thomas from St. Jude Children’s Research Hospital will discuss how he used single cell and spatial transcriptomics to discover the underlying mechanism of an inflammatory immune response in the lungs.

A close up shot of a thumb pointing to a pimple on a patch of bare skin

Skin Cells Can Transform To Help Fight Acne

Dan Robitzski | Mar 2, 2022 | 5 min read

A new study reveals that the fibroblasts in tissue surrounding acne infections play an active role in the body’s immune response—and that existing treatments help trigger them to do so.

Scientific illustration of a migrating breast cancer cell.

Breast Cancer Cells Churn Out Cholesterol to Fuel Metastasis

Alejandra Manjarrez, PhD | Feb 4, 2022 | 4 min read

A study uncovers a novel connection between the biomolecule and cancer progression.

CAR T Cells Mend Broken Mouse Hearts

Sophie Fessl, PhD | Jan 6, 2022 | 4 min read

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.

Identified: Molecular Predictors of Rheumatoid Arthritis Relapse

Ruth Williams | Jul 15, 2020 | 4 min read

The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.

cardiac fibrosis car t chimeric antigen receptor immunotherapy t cells fibroblasts cardiovascular disease

CAR T Immunotherapy May Find New Use in Treating Cardiac Fibrosis

Emma Yasinski | Sep 11, 2019 | 3 min read

Scientists show the approach can kill cells that cause hardening of heart tissue in mice.

Image of the Day: Scarred Hearts

Ashley Yeager | Dec 4, 2018 | 1 min read

Maps of diving cells before and after heart attacks in mice offer additional evidence against the existence of cardiac stem cells.

Image of the Day: Cooking Up Neurons

The Scientist Staff and The Scientist Staff | May 11, 2018 | 1 min read

Using different combinations of transcription factors, researchers create a diverse array of neurons from mouse skin cells.

Image of the Day: 3-D Nanofibers

The Scientist Staff and The Scientist Staff | Mar 7, 2018 | 1 min read

Researchers created a nanofibrous scaffold to see how it supports cell growth.

Image of the Day: Itty Bitty Cell Sucker

The Scientist Staff | Jul 21, 2017 | 1 min read

With a diameter smaller than 100 nanometers, this nanopipette’s indiscernible tip is tiny enough to suck up minute contents of a single cell.

With CRISPR, Scientists Make Neurons From Fibroblasts

Kerry Grens | Aug 15, 2016 | 1 min read

Researchers use the CRISPR/Cas system to express three transcription-factor genes, changing the identities of mouse cells.

Watching Cancer on the Move

Jef Akst | Dec 15, 2015 | 1 min read

Fibroblasts help tumors metastasize by paving a “migration highway” through the extracellular matrix, scientists report.

Highly Cited Stem Cell Paper Pulled

Kerry Grens | Aug 5, 2014 | 1 min read

The authors of a 2008 Nature paper have retracted it after new data watered down the conclusions.

Week in Review: February 24–28

Tracy Vence | Feb 28, 2014 | 3 min read

New PLOS data sharing rules; mouse cortical connectome published; reprogramming astrocytes into neurons and fibroblasts into hepatocytes

A Hair-Raising Solution?

Dan Cossins | Sep 1, 2013 | 4 min read

In the long-fought battle against baldness, researchers are finally identifying molecular pathways that can be manipulated to generate new hair follicles.