gene activity

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 

Look-alikes are also more likely to share lifestyle traits.

A new study has identified a molecular tradeoff between growth and immunity in moths in response to the administration of subtherapeutic doses of antibiotics, a common practice in animal husbandry.

Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.

In just 16 months, physicians went from identifying a novel rare disease in three-year-old Marley to successfully treating her with a drug previously used to treat African sleeping sickness and pediatric cancer.

A decade-long effort to probe gene regulation reveals differences between males and females, points to essential regulatory elements, and offers insight into past work on telomeres.

By bringing genetics into clinical medicine, the University of British Columbia medical geneticist helped to identify the gene mutations responsible for many rare diseases.

To see if the spiky fish shares signaling pathways found in other organisms, scientists scooped up specimens during a mating frenzy on the shores of Japan.

Worms with the reproduction-related TCER-1 gene deleted could fight off infection for longer and survived better when exposed to heat and radiation.

By unraveling the molecular underpinnings of inherited blood disorders, the Boston Children’s Hospital researcher has provided the basis for therapies now being tested for beta-thalassemia and sickle cell disease.

Developing computational tools to analyze the reams of microbial sequencing data his lab generates, the UC San Diego microbiologist is a pioneer of microbiome research.

The Carnegie Mellon computational biologist thinks machine learning algorithms can direct high-throughput experiments to solve the field’s unanswered questions.

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Scientists have manipulated the electrical signals that help guide flatworms in regenerating their body parts to encourage a flatworm to grow two heads.

Turning to molecular genetics, the Baylor pediatric neurologist and geneticist works to discover the biological basis for the rare neurological diseases she sees in her patients.

The medicine increases the activity of a deficient enzyme in certain patients with the condition.

RNA-sequencing data reveal that specific tissues have distinct changes in gene expression after an individual has passed away.