gene drive

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

United Nations members agree to some restrictions on the technology, but not a total suspension of its use.

No females were produced after eight generations, causing the population to collapse.

It’s the first demonstration of the technology in mammals.

Editors’ picks of the year’s best in The Scientist infographics.

In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.

A computer model estimates that gene-drive technology could wipe out populations of an invasive mammal on islands. 

Rare genetic variants could blunt efforts to destroy pest populations. 

Meet some of the people featured in the January 2017 issue of The Scientist.

Aedes and Anopheles control; three-parent babies; the PhD glut

Introducing genetic changes into mosquito populations could be key to effective malaria control.

For years, researchers have looked to genetically modify mosquitoes to prevent the spread of malaria. Now they have a promising strategy.

Activists claim the technology is too risky, but scientists advise the United Nations to continue to support gene drive research.

Scientists are getting to closer to developing a technique that can suppress mosquito populations on a continental scale, based on preliminary modeling results.

Researchers have identified the male-determining gene in the malaria mosquito, whose expression in females is lethal.

Using the precision gene-editing tool, researchers demonstrate an ability to create large populations of malaria parasite–resistant mosquitoes.

Researchers have developed two methods to avoid the unchecked spread of engineered genes through wild populations.

A powerful new CRISPR/Cas9 tool can be used to produce homozygous mutations within a generation, but scientists call for caution.