Gene Drive–Equipped Mosquitoes Released into Lab Environment
Gene Drive–Equipped Mosquitoes Released into Lab Environment
The large-scale experiments aim to test how the technology would fare in the wild, if deployed to knock down populations of the pests.
Gene Drive–Equipped Mosquitoes Released into Lab Environment
Gene Drive–Equipped Mosquitoes Released into Lab Environment

The large-scale experiments aim to test how the technology would fare in the wild, if deployed to knock down populations of the pests.

The large-scale experiments aim to test how the technology would fare in the wild, if deployed to knock down populations of the pests.

gene drive
First Successful Gene Drive in Mammals
First Successful Gene Drive in Mammals
Abby Olena | Jan 23, 2019
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
No Ban on Gene Drives: UN Convention
No Ban on Gene Drives: UN Convention
Kerry Grens | Nov 30, 2018
United Nations members agree to some restrictions on the technology, but not a total suspension of its use.
Study: Gene Drive Wipes Out Lab Mosquitoes
Study: Gene Drive Wipes Out Lab Mosquitoes
Ashley Yeager | Sep 24, 2018
No females were produced after eight generations, causing the population to collapse.
CRISPR Gene Drive Used to Alter Mouse Coat Color
CRISPR Gene Drive Used to Alter Mouse Coat Color
Shawna Williams | Jul 9, 2018
It’s the first demonstration of the technology in mammals.
The Best Multimedia of 2017
The Best Multimedia of 2017
Catherine Offord | Dec 27, 2017
Editors’ picks of the year’s best in The Scientist infographics.
Gene Drive Limitations
Gene Drive Limitations
Jef Akst | Oct 9, 2017
In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.
Driving Down Pests
Driving Down Pests
Amy Lewis | Aug 27, 2017
A computer model estimates that gene-drive technology could wipe out populations of an invasive mammal on islands. 
Gene Drive’s Achilles Heel
Gene Drive’s Achilles Heel
Kerry Grens | May 22, 2017
Rare genetic variants could blunt efforts to destroy pest populations. 
Contributors
Contributors
Ben Andrew Henry | Jan 1, 2017
Meet some of the people featured in the January 2017 issue of The Scientist.
Gene Drives and Other Controversies
Gene Drives and Other Controversies
Mary Beth Aberlin | Jan 1, 2017
Aedes and Anopheles control; three-parent babies; the PhD glut
Using Gene Drives to Limit the Spread of Malaria
Using Gene Drives to Limit the Spread of Malaria
Tony Nolan and Andrea Crisanti | Jan 1, 2017
Introducing genetic changes into mosquito populations could be key to effective malaria control.
Infographic: Using Gene Drive to Control Malaria
Infographic: Using Gene Drive to Control Malaria
Tony Nolan and Andrea Crisanti | Dec 31, 2016
For years, researchers have looked to genetically modify mosquitoes to prevent the spread of malaria. Now they have a promising strategy.
UN Rejects Calls for Moratorium on Gene Drive Research
UN Rejects Calls for Moratorium on Gene Drive Research
Joshua A. Krisch | Dec 22, 2016
Activists claim the technology is too risky, but scientists advise the United Nations to continue to support gene drive research.
Researchers Propose Solution to Gene Drive Technology Problem
Researchers Propose Solution to Gene Drive Technology Problem
Ben Andrew Henry | Nov 22, 2016
Scientists are getting to closer to developing a technique that can suppress mosquito populations on a continental scale, based on preliminary modeling results.
“Maleness” Gene Found in Malaria Mosquito
“Maleness” Gene Found in Malaria Mosquito
Anna Azvolinsky | Jun 30, 2016
Researchers have identified the male-determining gene in the malaria mosquito, whose expression in females is lethal.
CRISPR-Powered Malaria Mosquito Gene Drive
CRISPR-Powered Malaria Mosquito Gene Drive
Tracy Vence | Nov 24, 2015
Using the precision gene-editing tool, researchers demonstrate an ability to create large populations of malaria parasite–resistant mosquitoes.
Reining in Gene Drives
Reining in Gene Drives
Karen Zusi | Nov 18, 2015
Researchers have developed two methods to avoid the unchecked spread of engineered genes through wild populations.
CRISPR Chain Reaction
CRISPR Chain Reaction
Jenny Rood | Mar 19, 2015
A powerful new CRISPR/Cas9 tool can be used to produce homozygous mutations within a generation, but scientists call for caution.