gene silencing
Prominent Epigeneticist Dies
Prominent Epigeneticist Dies
Bob Grant | Mar 7, 2017
The National Cancer Institute’s Amar Klar uncovered many of the intricacies of gene silencing and other heritable epigenetic alterations.
Methylation Maestro
Methylation Maestro
Anna Azvolinsky | Jan 1, 2017
After initially discovering that DNA methylation represses transcription, Howard Cedar continues to explore how the epigenetic mark regulates gene expression.
Hidden Menace
Hidden Menace
John Frater, Genevieve Martin, Matthew Pace | May 1, 2015
Curing HIV means finding and eradicating viruses still lurking in the shadows.
Hide and Seek
Hide and Seek
The Scientist Staff | May 1, 2015
Oxford researcher John Frater explains the strategy of targeting viral reservoirs to beat HIV.
One Gene, Two Mutations
One Gene, Two Mutations
Tracy Vence | Nov 5, 2013
Knocking down a single gene spurs pronounced secondary effects in the yeast genome.
Gene Silencing Is Golden
Gene Silencing Is Golden
Carina Storrs | Aug 1, 2013
A beginner’s how-to on RNAi screening in mammalian cells
Dynamic Delivery
Ruth Williams | Jul 1, 2012
Microscopic sponges made entirely of RNA enable efficient gene silencing.
Delivering Silence
Sabrina Richards | Mar 1, 2012
Using RNA viruses to silence genes could optimize tissue targeting while reducing toxicity.
Unsilencing a Gene
Tia Ghose | Dec 21, 2011
Scientists have found a way to reactivate a gene in mice that is silenced in a neurodevelopmental disorder called Angelman syndrome.