early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

histone methylation

sperm epigenetics cancer risk heritability histones
Mice Inherit Cancer Susceptibility Via Epigenetic Changes in Sperm
Emma Yasinski | Apr 19, 2019
Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.
Plants’ Epigenetic Secrets
Jef Akst | Feb 1, 2017
Unlike animals, plants stably pass on their DNA methylomes from one generation to the next. The resulting gene silencing likely hides an abundance of phenotypic variation.
Infographic: Plant Methylation Basics
Jef Akst | Jan 31, 2017
Multiple molecular mechanisms keep plant DNA methylation in order.
Stockpiling Histones
Kerry Grens | Feb 1, 2013
Histones stored on lipid droplets in fly embryos provide a backup supply when newly synthesized ones are lacking.
The Epigenetic Lnc
Kevin V. Morris | Oct 1, 2012
Long non-protein-coding RNA (lncRNA) sequences are often transcribed from the opposite, or antisense, strand of a protein coding gene. In the past few years, research has shown that these lncRNAs play a number of regulatory roles in the cell. For exa
How Longevity Is Passed On
Cristina Luiggi | Oct 19, 2011
For the first time researchers have shown that epigenetic changes that increase lifespan can be inherited across multiple generations.
The Mark of Faith
Robert E. Kingston | Mar 1, 2011
Testing a central tenet of epigenetic regulation
Epigenetics—A Primer
Stefan Kubicek | Mar 1, 2011
There are many ways that epigenetic effects regulate the activation or repression of genes. Here are a few molecular tricks cells use to read off the right genetic program.
Epigenetics—A Primer
Stefan Kubicek | Mar 1, 2011
Epigenetic events regulate the activities of genes without changing the DNA sequence. Different genes are expressed depending on the methyl-marks attached to DNA itself and by changes in the structure and/or composition of chromatin.