New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

Researchers use base-editing to swap out an erroneous nucleotide responsible for a potentially life-threatening blood disorder.

Six scientists question the authors’ conclusions about the DNA repair process that led to the human embryos’ correction of a defective gene.

Scientists correct a mutation in fertilized eggs that causes a severe cardiac disease.

The embryos, whose genes were altered by CRISPR, were not intended for implantation. 

Scientists have created a high-resolution, 3-D atlas of human embryonic development during the first trimester of gestation.

World leaders agree to fight superbugs; researchers edit human embryos; peer reviewers’ motivations

A new culture system allows researchers to track the development of human embryos in vitro for nearly two weeks.

Researchers at the Francis Crick Institute in London will use CRISPR/Cas9 to modify genes in early human embryos.