humanized animals

Explore how humanized liver chimeric mouse models smooth the transition between the laboratory and clinical trials.

Can mice with humanlike tissues better model drug effects in people?

The animal world is full of clever solutions to bioengineering challenges.

Ethical issues attend the creation of animal-human chimeras.

A study suggests that some mouse models do not accurately mimic human molecular mechanisms of inflammatory response, but other mouse strains may fare better.

A German ethics council weighs in on the discussion about the use of human-animal chimeras in research.

A UK panel puts forth guidelines for research that use experimental animals harboring human cells and tissues.