A bacterium that produces an insulin-like peptide can give mice type 1 diabetes, and infection with the microbe seems to predict the onset of the disease in humans, a study finds.

The newly authorized intradermal vaccination only requires one-fifth of the usual vaccine dose. This will help stretch out the limited vaccine supply, experts say, but only if healthcare personnel receive sufficient training.

The Scientist asks Brigham and Women’s Hospital infectious disease specialist Lindsey Baden about testing for prior infections.

The results could help guide the design of new vaccines for the disease.

Researchers find that tissue-resident memory T cells in the corneas of mice engender a lasting immune response.

The work reveals that the pandemic flu was likely the direct predecessor of the seasonal H1N1 flu that circulated for decades.

A mouse study points to a possible mechanism by which the smallpox vaccine helped eradicate the disease in the 1980s.

The virus’s ability to slip directly from one cell to another may help it avoid some of the body’s immune responses.

A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.

If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.

President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  

This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.