When the Immune Response Makes COVID-19 Worse
When the Immune Response Makes COVID-19 Worse
If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.
When the Immune Response Makes COVID-19 Worse
When the Immune Response Makes COVID-19 Worse

If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.

If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.

immune response
Updated Oct 15
To Booster or Not: Scientists and Regulators Debate
To Booster or Not: Scientists and Regulators Debate
Jef Akst | Sep 16, 2021
President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Anthony King | Jul 1, 2021
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
Tuberculosis: The Forgotten Pandemic
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
Q&A: Human Challenge Studies of COVID-19 Underway in UK
Q&A: Human Challenge Studies of COVID-19 Underway in UK
Jef Akst | Jun 18, 2021
Researchers at Imperial College London and the University of Oxford are exposing healthy volunteers to SARS-CoV-2 for science.
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
T Cell–Boosting Zika Vaccine Protects Mice from the Virus
Ruth Williams | May 12, 2021
By avoiding the production of antibodies, something vaccines ordinarily induce, the immunization sidesteps the problem of antibody-dependent enhancement, which can amplify infection by a similar virus and is known to occur with dengue and Zika.
Antibody Spike Months After Ebola Infection Surprisingly Common
Antibody Spike Months After Ebola Infection Surprisingly Common
Catherine Offord | Jan 27, 2021
A study of people in Sierra Leone suggests that the virus can lie in hiding from the immune system before re-emerging later and sparking a new response—although researchers didn’t examine whether this could make people infectious again.
Infographic: How Vaccines Train Innate Immunity
Infographic: How Vaccines Train Innate Immunity
Shawna Williams | Nov 1, 2020
A recent study elucidates some of the changes that occur in the body after inoculation with a tuberculosis vaccine.
Steroid Drugs Are an Effective Treatment for Severe COVID-19: WHO
Steroid Drugs Are an Effective Treatment for Severe COVID-19: WHO
Catherine Offord | Sep 3, 2020
A meta-analysis of seven randomized controlled trials concludes that dexamethasone and other corticosteroids reduce 28-day mortality in seriously ill patients.
Blood Replacement Rescues Mice from Stroke Damage
Blood Replacement Rescues Mice from Stroke Damage
Amanda Heidt | Aug 31, 2020
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
Immune Biomarkers Tied to Severe COVID-19: Study
Immune Biomarkers Tied to Severe COVID-19: Study
Ruth Williams | Aug 19, 2020
Increases in the levels of three cytokines are among the features linked to poor outcomes.
Studies Report Rapid Loss of COVID-19 Antibodies
Studies Report Rapid Loss of COVID-19 Antibodies
Amanda Heidt | Jun 19, 2020
The results, while preliminary, suggest that survivors of SARS-CoV-2 infection may be susceptible to reinfection within weeks or months.
Could Curbing Runaway Immune Responses Treat COVID-19?
Could Curbing Runaway Immune Responses Treat COVID-19?
Shawna Williams | Apr 21, 2020
Drugs targeting patients’ immune systems, rather than the virus itself, could be key to recovery from severe cases of the disease, some researchers suggest.
Discovered: Metabolic Mechanism of Cytokine Storms
Discovered: Metabolic Mechanism of Cytokine Storms
Ruth Williams | Apr 15, 2020
By studying influenza in mice and cells, researchers identify a glucose metabolism pathway critical to the dysregulated immune response that kills many infectious disease patients, including those with COVID-19.
Scientists Study Vaping’s Harm as Second Death Reported
Scientists Study Vaping’s Harm as Second Death Reported
Nicoletta Lanese | Sep 5, 2019
In light of recent reports of electronic-cigarette–related illness and death, UNC Chapel Hill professor Robert Tarran discusses the dangerous effects of e-liquids on the lungs.
Image of the Day: White Blood Cell Webs
Image of the Day: White Blood Cell Webs
Emily Makowski | Sep 5, 2019
Neutrophil extracellular traps may hold clues to the cause of skin lesions in patients with a painful condition called hidradenitis suppurativa.
<em>C. elegans&nbsp;</em>Healthier Without Longevity Gene
C. elegans Healthier Without Longevity Gene
Chia-Yi Hou | Jul 17, 2019
Worms with the reproduction-related TCER-1 gene deleted could fight off infection for longer and survived better when exposed to heat and radiation.