Spleen-to-Liver Signals Control Systemic Inflammation
Spleen-to-Liver Signals Control Systemic Inflammation
In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.
Spleen-to-Liver Signals Control Systemic Inflammation
Spleen-to-Liver Signals Control Systemic Inflammation

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

infection
Sex Differences in Immune Responses to Viral Infection
Sex Differences in Immune Responses to Viral Infection
Catherine Offord | Mar 1, 2021
Stronger interferon production, greater T cell activation, and increased susceptibility to autoimmunity are just some of the ways that females seem to differ from males.
Infographic: How SARS-CoV-2 Immune Responses May Differ by Sex
Infographic: How SARS-CoV-2 Immune Responses May Differ by Sex
Catherine Offord | Mar 1, 2021
Males and females show differences in gene expression, cell activation, and antibody production in response to some viral infections, but whether these influence COVID-19 outcomes is still unclear.
Understanding Immune-Mediated Damage After Respiratory Infection
Understanding Immune-Mediated Damage After Respiratory Infection
The Scientist Creative Services Team in collaboration with 10x Genomics | Feb 17, 2021
Paul Thomas from St. Jude Children’s Research Hospital will discuss how he used single cell and spatial transcriptomics to discover the underlying mechanism of an inflammatory immune response in the lungs.
Infographic: How SARS-CoV-2 Might Travel from Mom to Fetus
Infographic: How SARS-CoV-2 Might Travel from Mom to Fetus
Ashley Yeager | Jan 1, 2021
The virus rarely spreads from mother to child before birth, but it can—and researchers are starting to investigate the path it takes.
Identifying PrognosticBiomarkers in COVID-19<br>
Identifying PrognosticBiomarkers in COVID-19
The Scientist Creative Services Team | Dec 21, 2020
Single-cell proteomics provides novel insights to COVID-19 disease progression
What&rsquo;s Killing Killer Whales? Autopsies Reveal a Role for Humans
What’s Killing Killer Whales? Autopsies Reveal a Role for Humans
Ashley Yeager | Dec 16, 2020
Stephen Raverty of the Ministry of Agriculture in Canada and Joseph Gaydos of UC Davis speak with The Scientist about their recent study assessing the causes of orca deaths.
Lipid Droplets Are Intracellular Bacteria-Fighting Machines
Lipid Droplets Are Intracellular Bacteria-Fighting Machines
Ruth Williams | Oct 15, 2020
Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.
Zika Infection Increases Risk of Severe Dengue Fever
Zika Infection Increases Risk of Severe Dengue Fever
Ruth Williams | Aug 27, 2020
A study of Nicaraguan children links prior Zika virus infection with aggravated dengue fever symptoms.
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Alakananda Dasgupta | Aug 26, 2020
The leaky blood vessels and lung fluid build-up in some COVID-19 patients might be explained by the virus’s corruption of an inflammation safeguard.
Bubonic Plague Cases Are No Cause for Panic
Bubonic Plague Cases Are No Cause for Panic
Chris Baraniuk | Jul 17, 2020
Reports of the infection—including one death this month—recently shook up social media. But, unlike COVID-19, plague is a disease that countries have more or less got under control.
SARS-CoV-2 Can Infect Human Brain Organoids
SARS-CoV-2 Can Infect Human Brain Organoids
Katarina Zimmer | Jul 9, 2020
The results are a proof-of-concept that the novel coronavirus can replicate in neurons, but it’s too soon to say whether this occurs in people with COVID-19.
Coronavirus-Infected Cells Grow Filopodia
Coronavirus-Infected Cells Grow Filopodia
Shawna Williams | Jun 30, 2020
SARS-CoV-2 causes cells to put out projections that spread the virus, a study finds.
Acceleration in New COVID-19 Cases in Some US States Causes Alarm
Acceleration in New COVID-19 Cases in Some US States Causes Alarm
Catherine Offord | Jun 23, 2020
Arizona, Florida, California, and others have seen record numbers of daily new coronavirus positives in the last couple of weeks, and that’s not just a reflection of more testing. Hospitalizations are up too.
Doctors Date First COVID-19 Case in France to Late December
Doctors Date First COVID-19 Case in France to Late December
Ashley Yeager | May 5, 2020
A retrospective analysis of stored respiratory samples shows one patient could have been infected with SARS-CoV-2 weeks before the coronavirus was thought to have arrived in France, but a critic of the result questions whether the sample was contaminated.
Discovered: Metabolic Mechanism of Cytokine Storms
Discovered: Metabolic Mechanism of Cytokine Storms
Ruth Williams | Apr 15, 2020
By studying influenza in mice and cells, researchers identify a glucose metabolism pathway critical to the dysregulated immune response that kills many infectious disease patients, including those with COVID-19.
Scientists Scan for Weaknesses in the SARS-CoV-2 Spike Protein
Scientists Scan for Weaknesses in the SARS-CoV-2 Spike Protein
Chris Baraniuk | Apr 9, 2020
The virus’s tool for prying open host cells is coated in a protective armor of sugar—but gaps may offer vulnerability to disruption by antibodies.
The COVID-19 Coronavirus May Travel in Aerosols
The COVID-19 Coronavirus May Travel in Aerosols
Amy Schleunes | Apr 3, 2020
Several studies have indicated that SARS-CoV-2 might be spread through air, but not all experts are convinced.
Laser-Triggered Nanobubbles Blast a Path into Biofilms
Laser-Triggered Nanobubbles Blast a Path into Biofilms
Jonathan Wosen | Apr 1, 2020
Researchers could one day use the method to deliver antibiotics to topical wounds infected by hard-to-treat masses of bacteria.
US Primate Centers Work to Protect Animals from COVID-19
US Primate Centers Work to Protect Animals from COVID-19
Ashley Yeager | Mar 19, 2020
Rhesus macaques can be infected with SARS-CoV-2, leading primate center scientists to try to prevent outbreaks in their colonies, especially as experiments on coronavirus start.