Researchers’ painstaking examinations have begun to reveal how the virus wreaks havoc in multiple organs and tissues.

Symptoms documented in cases of long COVID are wide ranging and variable.

A year and a half into the pandemic, the long-term effects of SARS-CoV-2 infection are garnering more research attention as millions of long COVID patients emerge.

In rats, the spleen directs a cytokine surge that drives system-wide inflammation, but it is not, as once believed, the main producer of the chemical messenger.

Stronger interferon production, greater T cell activation, and increased susceptibility to autoimmunity are just some of the ways that females seem to differ from males.

Males and females show differences in gene expression, cell activation, and antibody production in response to some viral infections, but whether these influence COVID-19 outcomes is still unclear.

The virus rarely spreads from mother to child before birth, but it can—and researchers are starting to investigate the path it takes.

Stephen Raverty of the Ministry of Agriculture in Canada and Joseph Gaydos of UC Davis speak with The Scientist about their recent study assessing the causes of orca deaths.

Far from being inert fat-storage depots within cells, these lipid-loaded organelles recruit immune proteins and block bacterial growth.

A study of Nicaraguan children links prior Zika virus infection with aggravated dengue fever symptoms.

The leaky blood vessels and lung fluid build-up in some COVID-19 patients might be explained by the virus’s corruption of an inflammation safeguard.

Reports of the infection—including one death this month—recently shook up social media. But, unlike COVID-19, plague is a disease that countries have more or less got under control.

The results are a proof-of-concept that the novel coronavirus can replicate in neurons, but it’s too soon to say whether this occurs in people with COVID-19.

SARS-CoV-2 causes cells to put out projections that spread the virus, a study finds.

Arizona, Florida, California, and others have seen record numbers of daily new coronavirus positives in the last couple of weeks, and that’s not just a reflection of more testing. Hospitalizations are up too.

A retrospective analysis of stored respiratory samples shows one patient could have been infected with SARS-CoV-2 weeks before the coronavirus was thought to have arrived in France, but a critic of the result questions whether the sample was contaminated.

By studying influenza in mice and cells, researchers identify a glucose metabolism pathway critical to the dysregulated immune response that kills many infectious disease patients, including those with COVID-19.

The virus’s tool for prying open host cells is coated in a protective armor of sugar—but gaps may offer vulnerability to disruption by antibodies.