lab mice

Mice rendered infertile through ovary cell–targeting mutations gave birth to seemingly normal offspring through natural mating after a virus-based gene therapy was injected into their ovaries.

A mouse study points to a possible mechanism by which the smallpox vaccine helped eradicate the disease in the 1980s.

The geneticist’s long career included leading the laboratory’s recovery from a devastating 1989 fire.

The Francis Crick Institute neurobiologist aims to learn how physiological states, such as hunger, alter information processing in the brain.

The agency plans to stop funding virtually all toxicology studies in mammals by 2035.

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

Becoming a neuroscientist with a service dog by your side presents numerous challenges. Joey Ramp, who went back to college to study her own post-traumatic stress disorder, is learning this the hard way.

It’s the first demonstration of the technology in mammals.

The results suggest the virus could severely alter brain development in infants infected after birth, but blocking a signaling protein early on might ease certain symptoms.

As Cape Town nears drying up, researchers there have come up with simple ways to dramatically cut back on water use.  

Pupil constriction during sleep may protect the murine brain from being awakened by sudden flashes of light.

Lab-grown muscle stem cells from mice mimic the formation of muscle fibers in vivo. 

Researchers have catalogued mutations in the coding regions of 36 of the most important mouse strains.

The cell-surface receptor, SIRP-alpha, initiates the innate immune response in hosts.  

Discrepancies in the populations’ immune systems suggest murine models of immunological disorders possess more limitations than scientists had appreciated.

A study links excess body weight in the rodents with dopamine receptor inactivity and reduced movement.

Mice that live in a more-stimulating environment for two weeks appear to develop a more-inflammatory immune state that might help protect the animals against infection. 

Researchers have identified a mutation in a commonly used commercial mouse strain that could impact experimental results.

A new drug shows promise as a weight-loss solution in mice, prompting the animals to burn calories in the absence of a meal.