A previously undetected pathway in the mouse brain bypasses the visual cortex to directly activate contagious itch.

Researchers say there may be similar, human genes whose effects on lifespan vary by sex.

The findings likely have implications for animal research far beyond the study of antidepressants.

A bacterium that produces an insulin-like peptide can give mice type 1 diabetes, and infection with the microbe seems to predict the onset of the disease in humans, a study finds.

An odorant found in the pee of pregnant mice—and in bananas—induces stress but also relieves pain in male mice, a study shows.

A study reveals a molecular pathway linking exercise to an amped-up immune response to pancreatic cancer and greater responsiveness to treatment.

Experiments in animals and observations in humans suggest that the amount of proline circulating in one’s plasma has a strong association with depression severity.

Microbes in the gut influence the death of support cells in the brain by producing isoamylamine, a study suggests.

A growth factor found in the cerebrospinal fluid of young mice triggered the proliferation of myelin-making cells when injected into the brains of older mice.

Mice rendered infertile through ovary cell–targeting mutations gave birth to seemingly normal offspring through natural mating after a virus-based gene therapy was injected into their ovaries.

A mouse study points to a possible mechanism by which the smallpox vaccine helped eradicate the disease in the 1980s.

The geneticist’s long career included leading the laboratory’s recovery from a devastating 1989 fire.

The Francis Crick Institute neurobiologist aims to learn how physiological states, such as hunger, alter information processing in the brain.

The agency plans to stop funding virtually all toxicology studies in mammals by 2035.

Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.

Becoming a neuroscientist with a service dog by your side presents numerous challenges. Joey Ramp, who went back to college to study her own post-traumatic stress disorder, is learning this the hard way.

It’s the first demonstration of the technology in mammals.

The results suggest the virus could severely alter brain development in infants infected after birth, but blocking a signaling protein early on might ease certain symptoms.

As Cape Town nears drying up, researchers there have come up with simple ways to dramatically cut back on water use.