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3D Illustration of X shaped chromosomes in blue
X Chromosome Silenced in Some Cancers in Males
A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 
X Chromosome Silenced in Some Cancers in Males
X Chromosome Silenced in Some Cancers in Males

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 

A study finds that XIST, the gene that shuts down one X chromosome in people who have two, is linked to cancer in males. 

long noncoding RNA
Cellular DNA and epigenetics
Do Epigenetic Changes Influence Evolution?
Katarina Zimmer | Nov 1, 2022 | 10+ min read
Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.
Conceptual image showing molecules making up a brain shape
The Noncoding Regulators of the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 10+ min read
Noncoding RNAs are proving to be critical players in the evolution of brain anatomy and cognitive complexity.
Illustration of RNAs
Infographic: Noncoding RNA in the Brain
Christie Wilcox, PhD | Sep 12, 2022 | 4 min read
Neurologically important noncoding RNAs come in many shapes and sizes.
An artist's rendition of an RNA molecule in light blue on a dark blue background
Same RNA Acts in Neurodegeneration and Cancer
Abby Olena, PhD | Oct 29, 2021 | 3 min read
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena, PhD | Aug 6, 2021 | 4 min read
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
small-molecule therapeutics treat cancer and other diseases
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Claire Asher | Apr 1, 2019 | 9 min read
Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.
Study: Most Long Noncoding RNAs Likely Functional
Kerry Grens | Mar 1, 2017 | 2 min read
Nearly 20,000 lncRNAs identified in human cells may play some role in cellular activities.
Managing Methylation
Karen Zusi | Jan 1, 2016 | 2 min read
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Not So Noncoding
Jenny Rood | Jun 1, 2015 | 2 min read
An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.
Nuclear Cartography
Jeffrey M. Perkel | Oct 1, 2014 | 8 min read
Techniques for mapping chromosome conformation
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