An artist's rendition of an RNA molecule in light blue on a dark blue background
Same RNA Acts in Neurodegeneration and Cancer
The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.
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Same RNA Acts in Neurodegeneration and Cancer
Same RNA Acts in Neurodegeneration and Cancer

The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.

The long noncoding RNA MINCR, implicated in ALS and Alzheimer’s disease as well as several types of cancer, appears to function differently when present at high versus low levels.

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long noncoding RNA

ribbon model of phenylalanine hydroxylase enzyme
Noncoding RNA Improves Symptoms in Mice with Metabolic Disorder
Abby Olena | Aug 6, 2021
A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.
small-molecule therapeutics treat cancer and other diseases
Scientists Take Aim at Disease-Causing RNAs Using Small-Molecule Drugs
Claire Asher | Apr 1, 2019
Renewed interest from the biotech industry sparks hope for drugging the nucleic acid to treat cancer and other conditions.
Study: Most Long Noncoding RNAs Likely Functional
Kerry Grens | Mar 1, 2017
Nearly 20,000 lncRNAs identified in human cells may play some role in cellular activities.
Managing Methylation
Karen Zusi | Jan 1, 2016
A long noncoding RNA associated with DNA methylation has the power to regulate colon cancer growth in vitro.
Not So Noncoding
Jenny Rood | Jun 1, 2015
An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.
Nuclear Cartography
Jeffrey M. Perkel | Oct 1, 2014
Techniques for mapping chromosome conformation