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Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment
The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.
Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment
Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment

The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.

The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.

metabolites
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Diabetes Marker Linked to COVID-19 Severity in Mice
Alejandra Manjarrez, PhD | May 16, 2022 | 3 min read
A sugar that’s less abundant in the blood of people with diabetes binds to SARS-CoV-2’s spike protein and disrupts the virus’s ability to fuse with cells.  
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Tinkering with Gut Microbes Boosts Brain Plasticity in Mice
Sophie Fessl, PhD | Jan 13, 2022 | 4 min read
Intestinal bacteria contribute to the effect of stimulating environments on the brain’s ability to adapt, a study concludes.
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A Nose by Any Other Name: Tracking the Scent of Tumor Metabolic Waste
Iris Kulbatski, PhD | 3 min read
The unique odor profiles of tumors can be used to develop diagnostic sensing tools.
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Distinct Microbiome and Metabolites Linked with Depression
Rachael Moeller Gorman | Dec 9, 2020 | 4 min read
The gastrointestinal tracts of people with major depressive disorder harbor a signature composition of viruses, bacteria, and their metabolic products, according to the most comprehensive genomic and metabolomic analysis in depression to date.
Nutrition Researchers Can Determine What You’ve Been Eating
Amber Dance | Dec 1, 2020 | 10+ min read
The study of diet, long plagued by inaccuracies in self reports, is entering a new age of precision with the methods of metabolomics.
Engineered Bacteria Make Tumors More T Cell-Friendly
Engineered Bacteria Make Tumors More T Cell-Friendly
Aparna Nathan | 5 min read
Microbes designed to produce specific immunomodulatory metabolites could give immunotherapy a boost.
Infographic: Deciphering Diet from Blood and Urine Samples
Amber Dance | Dec 1, 2020 | 1 min read
Nutrition researchers are beginning to use metabolomics to determine how healthy subjects’ diets are, and even to reveal specific properties of the foods they eat.
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Metabolites May Predict Lung Injury in 9/11 First Responders
Emma Yasinski | Sep 3, 2019 | 3 min read
Firefighters who didn’t develop obstructive airway disease after the World Trade Center attacks had higher levels of omega-3 fatty acids and other factors that hint at possible protective effects of diet.
Measuring Metabolites to Prevent, Diagnose, and Treat Cancer
Niki Spahich, PhD | 1 min read
Metabolomics research highlights molecules important for cancer prevention, diagnosis, and treatment.
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Image of the Day: Fluorescent Sharks
Nicoletta Lanese | Aug 13, 2019 | 1 min read
A newfound family of metabolites emits green light in response to the blue light of the deep ocean, causing certain sharks to glow.
an illustration of connections between the gut and heart
The Gut Microbiome Can Be a Boon or a Bane for Cardiovascular Health
Shawna Williams | Jul 10, 2019 | 5 min read
Researchers seek to untangle the biological mechanisms linking resident microbes to our hearts—and to harness them therapeutically.
The Community-Wide Effort to Standardize QA/QC for Metabolomics and Lipidomics
The Scientist Creative Services Team | 1 min read
Perspectives on the basics and future of QA/QC
High-Throughput Epigenetics Analyses
Jyoti Madhusoodanan | Jan 1, 2018 | 7 min read
Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.
Metabolomics Data Under Scrutiny
Ashley P. Taylor | Sep 15, 2017 | 4 min read
Out of 25,000 features originally detected by metabolic profiling of E. coli, fewer than 1,000 represent unique metabolites, a study finds.
Performing Metabolomic and Functional Proteomic Analyses on a Heterogenous Cancer Cell Population
The Scientist Creative Services Team in Collaboration with IsoPlexis | 2 min read
A tumor metabolome panel identifies altered cell states that lead to drug tolerance.
Altered Microbiome Contributes to Exaggerated Post-Diet Weight Regain in Mice
Tracy Vence | Nov 24, 2016 | 2 min read
Obesity-associated microbiome composition can persist after weight loss, affecting the exchange of metabolites between a mouse and its resident bugs, researchers report.
More than Water
Erin Weeks | Sep 6, 2013 | 1 min read
A comprehensive analysis of human urine identifies more than 3,000 metabolites. 
Obesity-Cancer Link Detailed
Chris Palmer | Jun 26, 2013 | 3 min read
Obesity drives an alteration of the gut microbiome, leading to the secretion of metabolites associated with the development of liver cancer.
“Breathprints” Could Diagnose Disease
Dan Cossins | Apr 5, 2013 | 2 min read
Researchers can identify individuals by the unique chemical signatures in their breath, suggesting that exhalations could be used for metabolomic tests.
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