MHC molecules

Researchers honed prediction models and datasets to unlock the potential of deep neural networks in biological applications while avoiding bias.

In human male-female pairs with a less similar suite of genes for human leukocyte antigens, sperm fare better when exposed to cervical mucus.

The Johns Hopkins University researcher bucked the prevailing idea that the body would not launch an immune response against its own tissues, and in doing so established an entirely new scientific discipline.

In most vertebrates, the absence of adaptive immunity would be catastrophic, but in some deep-sea angler fish species, it enables their “wild” and “wacky” mating habits.

The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.

Neoantigens may serve as valuable targets for new immunotherapies.

A second fatal, transmissible cancer has been identified in the already endangered species.  

With the iconic Australian marsupial carnivore on the brink of extinction, Tasmanian researchers race to unlock the immunological mysteries of a disease threatening the species.

See the devastating infectious cancer that may drive the Tasmanian Devil to extinction.

Philippa “Pippa” Marrack has made some unanticipated discoveries about how the immune system functions in health and disease.

The Nobel Prize winner who discovered the gene that encodes the major histocompatibility complex passes away at age 90.

Editor’s Choice in Immunology

Studying the earliest events in visual development, Carla Shatz has learned the importance of looking at one’s data with open eyes—and an open mind.