mitochondrial stress response

The Duke University cell biologist uses live-cell microscopy to reveal how brain cells rid themselves of damaged mitochondria and what goes wrong in neurodegenerative disease.

Researchers identified a novel mechanism by which chemically induced stress is “remembered” by the mitochondria of worms more than 50 generations after the original trigger.

Neurons stressed with chemicals produce Wnt, which in turn triggers changes in the germline.

Vesicles containing fragments of the organelles released from stressed adipocytes protect the heart against oxygen deprivation, a study in mice shows.

Scientists identify an inverse relationship between longevity in killifish and the expression of genes related to cellular respiration.

From plants to mice and human cells, tetracyclines lead to mitochondrial dysfunction in model organisms.

From DNA damage to cellular miscommunication, aging is a mysterious and multifarious process.

Researchers find that reducing mitochondrial protein production in some animals can increase lifespan by activating a protective stress response.