Broken DNA
DNA Damage Viewed with Unprecedented Clarity
A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.
DNA Damage Viewed with Unprecedented Clarity
DNA Damage Viewed with Unprecedented Clarity

A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.

A new tool called PRISM draws on virus-host interactions and a DNA repair pathway to help researchers visualize how cellular stress may contribute to neurodegenerative disease.

Modus Operandi
Conceptual image of blue neurons with glowing segments over blue background.
CRACK Method Reveals Novel Neuron Type in Mouse Brain
Dan Robitzski | Apr 18, 2022
A new technique reveals cells’ precise locations and functions in the brain. Its developers have already used it to identify a previously unknown neuron type.
Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
corals in water with fish
First Immortal Cell Line Cultured for Reef-Building Corals
Amanda Heidt | Jul 1, 2021
Lab-grown cells from the reef-building coral Acropora tenuis provide new opportunities to study bleaching, symbioses, and biomineralization.
liquid-containing tube labeled Laboratory Test Wastewater Sample SARS-CoV-2
Sewage Sampling Robots Speed SARS-CoV-2 Detection
Ruth Williams | May 1, 2021
An automated wastewater monitoring technique could enable researchers to predict outbreaks of the virus up to a week in advance.
Infographic: How to Ferret Out SARS-CoV-2 in Sewage
Ruth Williams | May 1, 2021
Researchers use magnetic nanoparticles and liquid-handling robots in an effort to detect COVID-19 outbreaks early.
Infographic: Light Triggers Photocage Opening, Apoptosis Inhibition
Jef Akst | Jan 1, 2021
Researchers develop a caspase inhibitor that only works after being irradiated with UV light, giving them control over apoptosis in human cells.
Light-Activated Molecules Stop Apoptosis at the Flip of a Switch
Jef Akst | Jan 1, 2021
A new inhibitor gives researchers the ability to control programmed cell death in cultured human T cells.
Infographic: Mix and Match
Ruth Williams | Jul 13, 2020
How llamas and superglue might lead to antiviral therapies
Bacterial Superglue Enables Antiviral Antibody Discovery
Ruth Williams | Jul 13, 2020
Testing out combinations of antiviral proteins from llamas could help researchers create potent virus-neutralizing multimers.
Infographic: Vaccines on Film
Ruth Williams | Jun 1, 2020
How an experimental preparation technique could make vaccines easier to transport, store, and administer
Vaccines Without Vials, Fridges, or Needles
Ruth Williams | Jun 1, 2020
A novel preparation technique could facilitate vaccine preservation, transportation, and administration.
Wrist-Mounted Air Pollution Detector
Claire Jarvis | May 1, 2020
A novel sampler records data on a broad range of environmental contaminants.
Infographic: Fashionable Detector
Claire Jarvis | May 1, 2020
Researchers set out to make an air pollution detector study subjects would want to wear.
Infographic: Transfection by Precision Cell Piercing
Ruth Williams | Apr 1, 2020
A microfluidic device creates a single hole in each cell to allow efficient DNA entry without compromising viability.
Precision Membrane Puncture Enables Efficient Cell Transfection
Ruth Williams | Apr 1, 2020
A device for piercing individual holes in cell membranes allows vector-free DNA delivery while maintaining cell viability.
Infographic: A Gene Editor for Plant Mitochondrial DNA
Ruth Williams | Mar 1, 2020
New TALEN-based tools enable the organelle’s genome to be targeted and modified.
Gene Editing Reaches Plant Mitochondria
Ruth Williams | Mar 1, 2020
Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.
an illustration of bacteria
Genome Data Enable Capture of Elusive Microbes
Ruth Williams | Jan 13, 2020
Using reverse genetics, researchers create antibodies to reel in previously uncultured bacteria.