Modus Operandi
Deep Pocket Exploration
Deep Pocket Exploration
Ruth Williams | Feb 1, 2017
A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.
Infographic: Modeling Molecules’ Receptor Binding
Infographic: Modeling Molecules’ Receptor Binding
Ruth Williams | Jan 31, 2017
A software upgrade follows ligands step-wise into their binding sites on receptors.
New Technique Enables Observation of Accessible Chromatin
New Technique Enables Observation of Accessible Chromatin
Ruth Williams | Jan 1, 2017
A test tube-based genome-labeling technique has been brought under the microscope.
Synthetic Sensors
Synthetic Sensors
Ruth Williams | Dec 1, 2016
Engineered circuits detect endogenous transcription factors to drive cellular outputs.
Infographic: How to Build a Synthetic Sensor
Infographic: How to Build a Synthetic Sensor
Ruth Williams | Nov 30, 2016
Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.
Neural Connectome Method Uses mRNA Barcodes
Neural Connectome Method Uses mRNA Barcodes
Ruth Williams | Nov 1, 2016
Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.
 
Genetic Tags Illuminate Where Neurons Extend
Genetic Tags Illuminate Where Neurons Extend
Ruth Williams | Oct 31, 2016
Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.
How to Track Translation in Living Cells
How to Track Translation in Living Cells
Ruth Williams | Oct 1, 2016
Four independent research groups develop techniques for visualizing peptide production in living cells.
Promoting Protein Partnerships
Promoting Protein Partnerships
Ruth Williams | Sep 1, 2016
Scientists generate new protein-protein interactions at an impressive PACE.
Protein or Perish
Protein or Perish
Ruth Williams | Aug 31, 2016
A bacteriophage must evolve certain variants of a protein or die.