A modification to traditional docking software enables the examination of a ligand’s passage into its receptor.

A software upgrade follows ligands step-wise into their binding sites on receptors.

A test tube-based genome-labeling technique has been brought under the microscope.

Engineered circuits detect endogenous transcription factors to drive cellular outputs.

Scientists designed a genetic sensor-and-readout system, based on detecting a transcription factor, that performs a custom cellular activity.

Researchers swap microscopy for RNA sequencing to track neural paths in the mouse brain.
 

Barcodes of mRNA travel to the cells' axon terminals, offering a sequencing-based approach to neural mapping.

Four independent research groups develop techniques for visualizing peptide production in living cells.

Scientists generate new protein-protein interactions at an impressive PACE.

A bacteriophage must evolve certain variants of a protein or die.