Personalized Cancer Vaccines Show Promise for Melanoma
Jef Akst | Jul 6, 2017
In two early trials, vaccines tailored to the mutations in individuals’ cancers appeared to protect 12 of 19 patients against relapse.
Cancer-Specific Antigens Encoded in “Junk” DNA
Cancer-Specific Antigens Encoded in “Junk” DNA
Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.
Researchers found that allegedly noncoding genetic material carries the instructions for many peptides that may help harness the immune system to fight cancer.
Contributors
Diana Kwon | Apr 1, 2017
Meet some of the people featured in the April 2017 issue of The Scientist.
Hitting It Out of the Park
Mary Beth Aberlin | Apr 1, 2017
Cancer can be as evasive and slippery as a spitball, but new immunotherapies are starting to connect.
Neoantigens Enable Personalized Cancer Immunotherapy
Stephen P. Schoenberger and Ezra Cohen | Apr 1, 2017
Tumors’ mutations can encode the seeds of their own destruction, in the form of immunogenic peptides recognized by T cells.
Infographic: Targeting Cancer Antigens
Stephen P. Schoenberger and Ezra Cohen | Mar 31, 2017
Neoantigens may serve as valuable targets for new immunotherapies.