Senior woman wearing a grey pullover, sitting on a bed, and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
ABOVE: © ISTOCK.COM, NICKYLLOYD
Early Inflammation Protects Against Chronic Pain, Study Finds
Early Inflammation Protects Against Chronic Pain, Study Finds

Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.

Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.

ABOVE: © ISTOCK.COM, NICKYLLOYD

neutrophils

A two-pronged needle, a glass vial of smallpox vaccine, and a syringe sit on a blue surface.
Smallpox Vaccine Recruits Skin Bacteria to Fight Disease
Patience Asanga | Apr 26, 2022
A mouse study points to a possible mechanism by which the smallpox vaccine helped eradicate the disease in the 1980s.
illustration of blue cancer cell extending tendrils around itself
Janus-Faced Neutrophils
Sophie Fessl | Mar 2, 2022
The immune cells facilitate healing, but they may also help tumors metastasize to the lungs after injury, a study in mice finds.
Checking Checkpoints for Treating Cancer
The Scientist Creative Services Team | Mar 31, 2021
Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.
neutrobots, neutrophils, white blood cells, microrobots, nanorobots, microbots, glioma, brain cancer, paclitaxel, magnetic, swarm, mice
Microscopic Robots Deliver Drugs to the Brain
Asher Jones | Mar 30, 2021
Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.
Special Report
covid-19 sars-cov-2 coronavirus pandemic immune response severity severe biomarkers prognostic predictor neutrophil monocyte myeloid cytokine interleukin
The Immune Hallmarks of Severe COVID-19
Katarina Zimmer | Sep 16, 2020
Researchers are trying to make sense of immune systems gone haywire and develop biomarkers to predict who will become the sickest from a coronavirus infection.
stroke, animal model, mouse model, blood, cytokine storm, immune system, immune response, MMP-9, neutrophil
Blood Replacement Rescues Mice from Stroke Damage
Amanda Heidt | Aug 31, 2020
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
neutrophil extracellular traps NETs coronavirus covid-19 pandemic sars-cov-2 innate immune response immunity pathogen elastase chromatin DNA
Neutrophil Extracellular Traps May Augur Severe COVID-19
Alakananda Dasgupta | May 28, 2020
These webs of chromatin and proteins, released by immune cells to control microbial infections, could serve as a therapeutic target in coronavirus infections.
Infographic: How NETs Work
Borko Amulic, Gabriel Sollberger | Oct 1, 2019
While neutrophil extracellular traps help guard the body from infection, they also can contribute to a range of diseases.
Why Immune Cells Extrude Webs of DNA and Protein
Borko Amulic, Gabriel Sollberger | Oct 1, 2019
Extracellular webs expelled by neutrophils trap invading pathogens, but these newly discovered structures also have ties to autoimmunity and cancer.
Image of the Day: White Blood Cell Webs
Emily Makowski | Sep 5, 2019
Neutrophil extracellular traps may hold clues to the cause of skin lesions in patients with a painful condition called hidradenitis suppurativa.
gallstones nets neutrophil extracellular traps
Immune “Webs” May Aid the Formation of Gallstones
Emma Yasinski | Aug 22, 2019
Researchers find evidence of neutrophil extracellular traps (NETs), sticky clumps of DNA and protein extruded by neutrophils, holding gallstones together.
Immunity in the Brain
Amanda B. Keener | Oct 31, 2016
Researchers document the diverse roles of immune cells in neuronal health and disease.
Week in Review: October 17–21
Jef Akst | Oct 20, 2016
Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds
Nixing NETs to Prevent Metastasis
Ruth Williams | Oct 19, 2016
Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.
Bacteria Assails Immune System with Toxin
Ben Andrew Henry | Oct 18, 2016
A Streptococcus bacterium invades the placenta with the aid of a neutrophil-puncturing pigment.
Tumor Traps
Kerry Grens | Apr 1, 2016
After surgery to remove a tumor, neutrophils recruited to the site spit out sticky webs of DNA that aid cancer recurrence.
Platelets Fan Inflammation
Kate Yandell | Dec 4, 2014
The circulating blood cells bind to neutrophils, prompting inflammation-related activity in these immune cell partners.
Video: March of the Neutrophils
Cristina Luiggi | Oct 13, 2010
Watch white blood cells as they scurry along blood vessels and descend upon an injury site.