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Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment
The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.
Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment
Mucus-Eating Gut Bacteria May Promote Fever After Cancer Treatment

The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.

The expansion of mucus-degraders in the mouse gut—possibly due to poor nutrition—thins the colon’s mucus layer and may weaken defenses against blood-infecting microbes.

neutrophils
Senior woman wearing a grey pullover sitting on a bed and holding her back.
Early Inflammation Protects Against Chronic Pain, Study Finds
Alejandra Manjarrez, PhD | May 12, 2022 | 3 min read
Human data and experiments in mice challenge the common use of anti-inflammatory drugs to treat pain.
A two-pronged needle, a glass vial of smallpox vaccine, and a syringe sit on a blue surface.
Smallpox Vaccine Recruits Skin Bacteria to Fight Disease
Patience Asanga | Apr 26, 2022 | 3 min read
A mouse study points to a possible mechanism by which the smallpox vaccine helped eradicate the disease in the 1980s.
GENETIC PREDISPOSITION TO VITAMIN D DEFICIENCY CONTRIBUTES TO SEVERE COVID-19
Genetic Predisposition to Vitamin D Deficiency Contributes to Severe COVID-19
Iris Kulbatski, PhD | 4 min read
Ana Teresa Freitas discusses how individual variation in vitamin D synthesis and metabolism influences susceptibility to upper respiratory viruses.
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Janus-Faced Neutrophils
Sophie Fessl, PhD | Mar 2, 2022 | 4 min read
The immune cells facilitate healing, but they may also help tumors metastasize to the lungs after injury, a study in mice finds.
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Microscopic Robots Deliver Drugs to the Brain
Asher Jones | Mar 30, 2021 | 5 min read
Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.
The balance of mind and body on a seesaw
Psychological Stress Distracts the Immune System from Fighting Infections
Jennifer Zieba, PhD | 3 min read
Acute stress makes immune cells migrate immediately to the bone marrow, which prepares the body for injury at the expense of increasing infectious disease susceptibility.
Special Report
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The Immune Hallmarks of Severe COVID-19
Katarina Zimmer | Sep 16, 2020 | 10+ min read
Researchers are trying to make sense of immune systems gone haywire and develop biomarkers to predict who will become the sickest from a coronavirus infection.
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Blood Replacement Rescues Mice from Stroke Damage
Amanda Heidt | Aug 31, 2020 | 5 min read
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
Checking Checkpoints for Treating Cancer
The Scientist Creative Services Team | 1 min read
Researchers devise strategies to improve checkpoint inhibitor therapy and predict patient response.
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Neutrophil Extracellular Traps May Augur Severe COVID-19
Alakananda Dasgupta | May 28, 2020 | 6 min read
These webs of chromatin and proteins, released by immune cells to control microbial infections, could serve as a therapeutic target in coronavirus infections.
Infographic: How NETs Work
Borko Amulic and Gabriel Sollberger | Oct 1, 2019 | 3 min read
While neutrophil extracellular traps help guard the body from infection, they also can contribute to a range of diseases.
Why Immune Cells Extrude Webs of DNA and Protein
Borko Amulic and Gabriel Sollberger | Oct 1, 2019 | 10 min read
Extracellular webs expelled by neutrophils trap invading pathogens, but these newly discovered structures also have ties to autoimmunity and cancer.
Image of the Day: White Blood Cell Webs
Emily Makowski | Sep 5, 2019 | 1 min read
Neutrophil extracellular traps may hold clues to the cause of skin lesions in patients with a painful condition called hidradenitis suppurativa.
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Immune “Webs” May Aid the Formation of Gallstones
Emma Yasinski | Aug 22, 2019 | 3 min read
Researchers find evidence of neutrophil extracellular traps (NETs), sticky clumps of DNA and protein extruded by neutrophils, holding gallstones together.
Immunity in the Brain
Amanda B. Keener | Oct 31, 2016 | 2 min read
Researchers document the diverse roles of immune cells in neuronal health and disease.
Week in Review: October 17–21
Jef Akst | Oct 20, 2016 | 2 min read
Report finds that pathologist involved in anonymous defamation case committed multiple acts of misconduct; growing eggs from stem cells; neutrophils’ role in metastasis; convergent evolution in birds
Nixing NETs to Prevent Metastasis
Ruth Williams | Oct 19, 2016 | 3 min read
Researchers discover that neutrophil extracellular traps help cancers spread, and design enzyme-loaded nanoparticles to destroy them.
Bacteria Assails Immune System with Toxin
Ben Andrew Henry | Oct 18, 2016 | 2 min read
A Streptococcus bacterium invades the placenta with the aid of a neutrophil-puncturing pigment.
Tumor Traps
Kerry Grens | Apr 1, 2016 | 2 min read
After surgery to remove a tumor, neutrophils recruited to the site spit out sticky webs of DNA that aid cancer recurrence.
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