noncoding RNA

The concept of epigenetic inheritance has long been controversial. Some researchers hope that new data on cross-generational effects of environmental exposures will help settle the debate.

A long noncoding RNA from humans appeared to help the enzyme phenylalanine hydroxylase work better in a mouse model of phenylketonuria, the disorder characterized by reduced activity of that enzyme.

Prior to a 2019 preprint, “glycoRNAs” weren’t known to exist. Now, the researchers who found them say they’re on lots of cells and may play a role in immune signaling.

The recently discovered long noncoding RNAs seem to boost the production of specific proteins in the cell by interacting with RNA-binding proteins, researchers find.

Injecting molecules from a sea slug that received tail shocks into one that didn’t made the recipient animal behave more cautiously. 

Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.

Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.
 

Nearly 20,000 lncRNAs identified in human cells may play some role in cellular activities.

From whole cells to genes, closer examination continues to surprise.
 

Bits of the transcriptome once believed to function as RNA molecules are in fact translated into small proteins.

Researchers scour the genome for micropeptides encoded within RNAs presumed to function in a noncoding capacity.

Newer CRISPR tools for manipulating transcription will help unlock noncoding RNA’s many roles.

Moderately obese men display different epigenetic marks on their sperm than lean men, and bariatric surgery in massively obese men correlated with changes in sperm methylation.

Scientists discover a novel antibacterial molecule that targets a vital RNA regulatory element.

Reconstructing the past using ancient DNA

An RNA thought to be noncoding in fact encodes a small protein that regulates calcium uptake in muscle.

The same microRNAs can have opposing roles in cancer.

Researchers have mapped the times of day when mouse genes are transcribed across 12 organs.

A groundbreaker in the study of Listeria monocytogenes, Pascale Cossart continues to build her research tool kit to understand how to fight such intracellular human pathogens.